Sorbitan monooleate (CAS 1338-43-8) — Citrus N/A Note Fragrance Ingredient

Citrus · Floral

Sorbitan monooleate

CAS 1338-43-8

Origin
synthetic
Note
N/A
IFRA
Generally safe
Data as of: Apr 2026

What Is Sorbitan monooleate?

Sorbitan monooleate is a synthetic emulsifier commonly found in cosmetics, pharmaceuticals, and food products. It helps blend oil and water components in creams, lotions, and processed foods. While not a fragrance ingredient itself, it plays a crucial role in stabilizing scented products. This ingredient ensures your favorite perfumes and lotions maintain their texture and scent consistency over time.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Approved for food and cosmetic use
Non-toxic and biodegradable
CAS
1338-43-8
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does Sorbitan monooleate Smell Like?

Sorbitan monooleate is odorless and does not contribute directly to fragrance profiles. As an emulsifier, it functions behind the scenes to stabilize scent compositions without altering their olfactory characteristics. Its molecular structure allows it to bind both hydrophilic and hydrophobic compounds, creating uniform dispersions that maintain fragrance integrity in complex formulations.

Layer 2

2D Molecular Structure

Sorbitan, mono-(9Z)-9-octadecenoate

SMILES: CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O

Chemistry, Properties & Perfumer Guide

The Chemistry

Sorbitan monooleate is a nonionic surfactant derived from sorbitol and oleic acid through esterification. This amphiphilic molecule contains both hydrophilic sorbitol groups and hydrophobic oleic acid chains, giving it excellent emulsifying properties. Industrially produced through controlled reactions between sorbitol and fatty acids, it’s part of the broader sorbitan ester family widely used in food, cosmetic, and pharmaceutical applications.

Physical & Chemical Properties

AppearanceAmber viscous liquid
SolubilitySoluble in oils, dispersible in water

Perfumer Guide

Note Position
N/A
Volatility
N/A
Blending
Functional additive
ApplicationTypical %RangeNotes
Emulsions1-5%0.5-10%Primary emulsifier
Fragrance Fixatives0.5-2%0.1-5%Stabilizes volatile compounds

Classic Accords

Tip: Use with polysorbates for optimal HLB balance in fragrance emulsions.

Alternatives & Comparisons

1
Polysorbate 80 CAS 9005-65-6

More water-soluble alternative when higher HLB values are needed in fragrance formulations.

2
Sorbitan monolaurate CAS 1338-39-2

Shorter chain length provides different emulsification properties for specific fragrance systems.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not restricted by IFRA – classified as processing aid rather than fragrance ingredient.

RIFM Assessment

Not evaluated by RIFM as it’s not a direct fragrance material.

Sustainability

Sorbitan monooleate is petroleum-derived but considered environmentally benign due to its biodegradability. Current production relies on conventional chemical synthesis, though some manufacturers are exploring bio-based sorbitol routes. Its efficient usage levels and non-toxic profile make it a relatively sustainable choice for emulsion stabilization.

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References

  1. European Food Safety Authority. (2015). Scientific Opinion on sorbitan esters. EFSA Journal. EFSA Journal 13(5)

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID6027397

Physical Properties

Molecular Weight 428.61 g/mol🔬 EPA CompTox
Density 1.077 g/cm^3📊 OPERA
Boiling Point 483.503 °C📊 OPERA
Melting Point 73.859 °C📊 OPERA
Flash Point 206.092 °C📊 OPERA
Refractive Index 1.506 Dimensionless📊 OPERA
Molar Volume 401.06 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 5.485 Log10 unitless📊 OPERA
LogD (pH 5.5) 5.33 Log10 unitless📊 OPERA
LogD (pH 7.4) 5.48 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 9.36 Log10 unitless📊 OPERA
Water Solubility 0 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0 mmHg📊 OPERA
Viscosity 180.829 cP📊 OPERA
Surface Tension 40.89 dyn/cm📊 OPERA
Thermal Conductivity 182.027 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 96.22 Ų💻 Computed
H-Bond Donors 3 count💻 Computed
H-Bond Acceptors 6 count💻 Computed
Rotatable Bonds 18 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 119.224 cm^3/mol📊 OPERA
Polarizability 47.264 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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