Tetrahydro-2-(p-tolyloxy)-2H-pyrane (CAS 13481-09-09) — Woody Middle Note Fragrance Ingredient

Woody · Floral

Tetrahydro-2-(p-tolyloxy)-2H-pyrane

CAS 13481-09-09

Origin
synthetic
Note
Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Tetrahydro-2-(p-tolyloxy)-2H-pyrane?

Tetrahydro-2-(p-tolyloxy)-2H-pyrane is a synthetic fragrance ingredient used in modern perfumery. It contributes to complex floral and woody accords. This molecule is typically found in niche fragrances where unique synthetic notes are prized for their stability and versatility.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Check for individual sensitivity
CAS
13481-09-09
Formula
Mixture
MW
Variable
Odor Family
Woody · Floral
Layer 1 · Enthusiast

What Does Tetrahydro-2-(p-tolyloxy)-2H-pyrane Smell Like?

Tetrahydro-2-(p-tolyloxy)-2H-pyrane offers a subtle blend of floral and woody nuances with a faintly sweet undertone. The scent evolves from a crisp, slightly herbal opening to a warm, woody dry-down, reminiscent of aged paper and distant forest floors.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Tetrahydro-2-(p-tolyloxy)-2H-pyrane is a synthetic pyran derivative. It is typically synthesized through the reaction of p-cresol with dihydropyran under acidic conditions. The molecule features a pyran ring ether-linked to a p-tolyl group, contributing to its stability and unique olfactory profile.

Physical & Chemical Properties

Boiling PointN/A
DensityN/A

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 10%Adds woody-floral complexity

Classic Accords

Tip: Use to enhance woody notes without overpowering floral elements.

Alternatives & Comparisons

1
Dihydrocoumarin CAS 119-84-6

Offers similar woody notes with added sweetness.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently apply.

RIFM Assessment

No specific RIFM assessment found.

Sustainability

As a synthetic molecule, Tetrahydro-2-(p-tolyloxy)-2H-pyrane is produced in controlled laboratory settings, minimizing environmental impact compared to some natural extracts. Its synthetic origin ensures consistent quality and reduces reliance on natural resources.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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