1,4-Butanediamine, N-(3-aminopropyl)- (CAS 124-20-9) — Citrus Not applicable Note Fragrance Ingredient

Citrus · Floral

1,4-Butanediamine, N-(3-aminopropyl)-

CAS 124-20-9

Origin
synthetic
Note
Not applicable
IFRA
Professional use
Data as of: Apr 2026

What Is 1,4-Butanediamine, N-(3-aminopropyl)-?

1,4-Butanediamine, N-(3-aminopropyl)- is a synthetic chemical used in industrial applications and specialty chemical formulations. It is not commonly encountered in consumer products but may be found in certain technical or niche applications. While not a typical fragrance ingredient, it serves as a building block in the synthesis of more complex compounds used in various industries.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Not intended for consumer use
Handle with protective equipment
CAS
124-20-9
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does 1,4-Butanediamine, N-(3-aminopropyl)- Smell Like?

This compound is not typically used for its odor profile in fragrance applications. As a synthetic amine, it may have a sharp, chemical odor characteristic of aliphatic amines, which are generally not pleasant or desirable in perfumery. Its primary use is as an intermediate in chemical synthesis rather than as a fragrance ingredient.

Layer 2

2D Molecular Structure

N-(3-Aminopropyl)-4-aminobutylamine

SMILES: NCCCCNCCCN

Chemistry, Properties & Perfumer Guide

The Chemistry

1,4-Butanediamine, N-(3-aminopropyl)- is a synthetic aliphatic diamine compound. It belongs to the class of polyamines and is primarily used as a chemical intermediate. The compound features multiple amine functional groups, making it reactive and useful in polymerization and other synthetic processes. Its synthesis typically involves the alkylation of amines or reduction of corresponding nitriles.

Physical & Chemical Properties

Boiling PointNot available
DensityNot available

Perfumer Guide

Note Position
Not applicable
Volatility
Not applicable
Blending
Not applicable
ApplicationTypical %RangeNotes
IndustrialNot applicableNot applicableChemical intermediate

Classic Accords

Tip: This compound is not recommended for use in fragrance formulations.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not regulated by IFRA as it is not a fragrance ingredient.

RIFM Assessment

Not assessed by RIFM as it is not a fragrance material.

Sustainability

As an industrial chemical intermediate, sustainability considerations focus on production efficiency and waste reduction. Being synthetic, it doesn’t involve agricultural sourcing but requires energy-intensive manufacturing processes. Proper handling and disposal are important to minimize environmental impact.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 124-20-9

    Physical Properties

    Molecular Weight145.25 g/mol🔬 PubChem
    LogP (Octanol-Water)-1🔬 PubChem
    Boiling Point129 °C🔬 EPA CompTox
    log Kp (skin permeability)-4.296💻 Calculated
    SMILESC(CCNCCCN)CN🔬 PubChem

    Volatility & Performance

    Fragrance NoteTop💻 Calculated

    Odor & Flavor

    Functional Groupsamine💻 RDKit

    Sensory Thresholds

    Odor Detection Threshold129 ppm📖 van Gemert
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID4036645

    Physical Properties

    Molecular Weight 145.25 g/mol🔬 EPA CompTox
    Density 0.925 g/cm^3🔬 EPA CTX
    Boiling Point 241.132 °C📊 OPERA
    Melting Point 23.688 °C🔬 EPA CTX
    Flash Point 123.606 °C📊 OPERA
    Refractive Index 1.475 Dimensionless📊 OPERA
    Molar Volume 160.254 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) -0.479 Log10 unitless📊 OPERA
    LogD (pH 5.5) -5.608 Log10 unitless📊 OPERA
    LogD (pH 7.4) -4.569 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 7.89 Log10 unitless📊 OPERA
    Water Solubility 3.274 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0.011 mmHg📊 OPERA
    Viscosity 5.237 cP📊 OPERA
    Surface Tension 33.534 dyn/cm📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 64.07 Ų💻 Computed
    H-Bond Donors 3 count💻 Computed
    H-Bond Acceptors 3 count💻 Computed
    Rotatable Bonds 7 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 45.144 cm^3/mol📊 OPERA
    Polarizability 17.897 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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