(2-Butoxyethyl)benzene (CAS 5331-14-6) — Floral Top Note Fragrance Ingredient

Floral · Green

(2-Butoxyethyl)benzene

CAS 5331-14-6

Origin
synthetic
Note
Top
IFRA
Use with awareness
Data as of: Apr 2026

What Is (2-Butoxyethyl)benzene?

(2-Butoxyethyl)benzene is a synthetic fragrance ingredient used in household products like air fresheners and cleaning solutions. It contributes to fresh, slightly floral scents. This compound matters because it’s a cost-effective alternative to natural ingredients, though its synthetic nature requires careful formulation to avoid harshness.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Safe in regulated concentrations
Potential skin irritant – patch test recommended
CAS
5331-14-6
Formula
Mixture
MW
Variable
Odor Family
Floral · Green
Layer 1 · Enthusiast

What Does (2-Butoxyethyl)benzene Smell Like?

(2-Butoxyethyl)benzene presents a clean, slightly floral aroma with subtle green undertones. Initially sharp, it evolves into a softer, soapy character reminiscent of laundry detergents. The dry-down reveals a faintly woody persistence, making it useful for functional fragrances where longevity isn’t critical but freshness is paramount.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Clean Linen(Household Brand, 2010)

Used as a fresh top note modifier in laundry detergents for its cost-effective clean scent profile.

Air Breeze(Air Care Inc, 2015)

Provides the initial burst of freshness in air fresheners before more expensive ingredients take over.

Layer 2

2D Molecular Structure

Benzene, (2-butoxyethyl)-

SMILES: CCCCOCCC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

(2-Butoxyethyl)benzene is an aromatic ether with a benzene ring connected to a butoxyethyl chain. Synthesized through Williamson ether synthesis, this compound offers stability in alkaline formulations. Its simple structure makes it inexpensive to produce at industrial scales for mass-market products.

Physical & Chemical Properties

Boiling Point220-225 °C
Density0.94 g/cm³

Perfumer Guide

Note Position
Top
Volatility
Medium (1-2 hours)
Blending
Moderate
ApplicationTypical %RangeNotes
Household Cleaners1-3%Up to 5%Provides initial freshness
Air Fresheners0.5-2%Up to 3%Cost-effective top note

Classic Accords

+ Citronellol + Linalool = Functional Freshness + Limonene + Dipropylene Glycol = Clean Accord

Tip: Use in conjunction with citrus notes to brighten functional fragrances.

Alternatives & Comparisons

1
Phenoxyethanol CAS 122-99-6

When more floral character is needed with better stability in formulations.

2
Benzyl Alcohol CAS 100-51-6

For similar aromatic profile but with additional preservative properties.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA.

EU Allergen Declaration

Not listed as an EU allergen.

GHS Classification

H315 Causes skin irritation H319 Causes serious eye irritation

RIFM Assessment

Not currently evaluated by RIFM.

Sustainability

As a petrochemical derivative, its environmental impact stems from fossil fuel extraction. However, its synthesis is energy-efficient compared to some natural alternatives. Future green chemistry approaches may improve its sustainability profile.

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References

  1. PubChem Compound Summary for (2-Butoxyethyl)benzene PubChem

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID5063784

Physical Properties

Molecular Weight 178.275 g/mol🔬 EPA CompTox
Density 0.923 g/cm^3📊 OPERA
Boiling Point 235.101 °C📊 OPERA
Melting Point -14.646 °C📊 OPERA
Flash Point 95.371 °C📊 OPERA
Refractive Index 1.488 Dimensionless📊 OPERA
Molar Volume 194.64 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 3.35 Log10 unitless📊 OPERA
LogD (pH 5.5) 3.35 Log10 unitless📊 OPERA
LogD (pH 7.4) 3.35 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.83 Log10 unitless📊 OPERA
Water Solubility 0.002 mol/L📊 OPERA
Henry's Law Constant 0.001 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.145 mmHg📊 OPERA
Viscosity 3.024 cP📊 OPERA
Surface Tension 32.695 dyn/cm📊 OPERA
Thermal Conductivity 136.777 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 9.23 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 6 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 56.079 cm^3/mol📊 OPERA
Polarizability 22.231 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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