2-Pentylcyclopentan-1-one (CAS 4819-67-4) — Floral Top to Middle Note Fragrance Ingredient

Floral · Sweet

2-Pentylcyclopentan-1-one

CAS 4819-67-4

Origin
synthetic
Note
Top to Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is 2-Pentylcyclopentan-1-one?

2-Pentylcyclopentan-1-one is a synthetic fragrance ingredient used in perfumes and scented products to add fruity, floral, and slightly woody notes. It is commonly found in air fresheners, detergents, and personal care products. This ingredient matters because it enhances the overall scent profile, providing a pleasant and long-lasting aroma that improves user experience.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Check for individual sensitivity
CAS
4819-67-4
Formula
Mixture
MW
Variable
Odor Family
Floral · Sweet
Layer 1 · Enthusiast

What Does 2-Pentylcyclopentan-1-one Smell Like?

2-Pentylcyclopentan-1-one offers a complex olfactory profile, starting with a fresh, fruity top note reminiscent of ripe apples and pears. As it evolves, it reveals a floral heart with hints of jasmine and rose, settling into a subtle woody base. The dry-down is smooth and slightly sweet, making it versatile for various fragrance applications.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Fruity Floral(Generic Brand, 2010)

Used to enhance the fruity and floral notes, providing a balanced and appealing scent.

Layer 2

2D Molecular Structure

2-Pentylcyclopentanone

SMILES: CCCCCC1CCCC1=O

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Pentylcyclopentan-1-one is a synthetic ketone with a cyclopentanone core and a pentyl side chain. It is produced through chemical synthesis, often involving the cyclization of appropriate precursors. The molecule’s structure contributes to its fruity and floral olfactory characteristics, making it a valuable ingredient in perfumery.

Physical & Chemical Properties

Boiling PointN/A
DensityN/A

Perfumer Guide

Note Position
Top to Middle
Volatility
Medium (1-2 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance2-5%Up to 10%Adds fruity and floral complexity
Personal Care1-3%Up to 5%Provides a pleasant scent

Classic Accords

Tip: Use in combination with other fruity and floral notes to enhance complexity.

Alternatives & Comparisons

1
2-Hexylcyclopentan-1-one CAS XXX-XX-X

Offers a similar profile with a slightly longer-lasting effect.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No current IFRA restrictions.

EU Allergen Declaration

Not listed as an EU allergen.

RIFM Assessment

No specific RIFM safety assessment found.

Sustainability

As a synthetic ingredient, 2-Pentylcyclopentan-1-one is produced in controlled environments, reducing the environmental impact compared to natural extraction. Its production can be optimized for minimal waste and energy use.

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References

  1. PubChem Compound Summary for 2-Pentylcyclopentan-1-one PubChem

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 4819-67-4

Physical Properties

Molecular Weight154.25 g/mol🔬 PubChem
LogP (Octanol-Water)2.9🔬 PubChem
Boiling Point220.9 °C🔬 EPA CompTox
Vapor Pressure0.1155 mmHg @ 25°C📊 OPERA
Flash Point89.8 °C🔬 EPA CompTox
Involatility Index0.01💻 Calculated
log Kp (skin permeability)-1.582💻 Calculated
SMILESCCCCCC1CCCC1=O🔬 PubChem

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassVery slow💻 Calculated
Persistence Score1.6 / 5💻 Calculated

Odor & Flavor

Functional Groupsketone💻 RDKit

Trade Names

Fleuramone (IFF), Projasmon P (Symrise).📖 Surburg
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID1044566

Physical Properties

Molecular Weight 154.253 g/mol🔬 EPA CompTox
Density 0.89 g/cm^3🔬 EPA CTX
Boiling Point 220.85 °C🔬 EPA CTX
Melting Point 9.992 °C📊 OPERA
Flash Point 85.6 °C🔬 EPA CTX
Refractive Index 1.451 Dimensionless📊 OPERA
Molar Volume 172.306 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 3.28 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 2.976 Log10 unitless📊 OPERA
LogD (pH 7.4) 2.976 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.24 Log10 unitless📊 OPERA
Water Solubility 0.004 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.116 mmHg🔬 EPA CTX
Viscosity 2.003 cP📊 OPERA
Surface Tension 30.792 dyn/cm📊 OPERA
Thermal Conductivity 133.634 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 4 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 46.414 cm^3/mol📊 OPERA
Polarizability 18.4 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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