6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-7-(1-methylethyl)- (CAS 62406-73-9) — Woody Base Note Fragrance Ingredient

Woody · Balsamic

6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-7-(1-methylethyl)-

CAS 62406-73-9

Origin
synthetic
Note
Base
IFRA
Generally safe
Data as of: Apr 2026

What Is 6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-7-(1-methylethyl)-?

6,10-Dioxaspiro[4.5]decane is a synthetic fragrance ingredient used in modern perfumery to add woody, spicy, or ambery nuances. It’s typically found in fine fragrances and personal care products where a sophisticated base note is desired. This molecule matters because it helps perfumers create complex scent profiles with excellent longevity, often serving as a subtle backbone in oriental and woody compositions without overpowering other notes.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major safety concerns in current use
Limited toxicological data available
CAS
62406-73-9
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does 6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-7-(1-methylethyl)- Smell Like?

This synthetic molecule presents a nuanced woody-spicy character with subtle ambery undertones. The opening reveals a crisp, almost ozonic freshness that quickly transitions into a warm heart reminiscent of aged cedarwood with a whisper of cardamom. As it dries down, it develops a sophisticated musk-like persistence that blends seamlessly with oriental accords. The overall effect is like polished antique wood furniture in a sunlit library – warm, refined, and slightly mysterious.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

6,10-Dioxaspiro[4.5]decane belongs to the spirocyclic ether class of compounds, characterized by their unique oxygen-containing ring systems. These structures are typically synthesized through acid-catalyzed cyclization reactions of appropriate diols or epoxy compounds. The specific substitution pattern on this molecule creates steric hindrance that influences its volatility and odor profile. While not found in nature, its structural motifs resemble certain degraded terpenoids found in aged wood resins.

Physical & Chemical Properties

Molecular WeightNot available
Boiling PointNot available

Perfumer Guide

Note Position
Base
Volatility
Low (6+ hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Used as base note fixative
Body Care0.5-1.5%Up to 2%Adds warmth to lotions
Home Fragrance2-4%Up to 6%Long-lasting woody note

Classic Accords

Tip: Use to add depth and longevity to woody compositions without excessive sweetness.

Alternatives & Comparisons

1
Iso E Super CAS 54464-57-2

More widely available woody-amber with similar fixative properties but stronger projection.

2
Vertofix Coeur CAS 68039-49-6

Offers comparable woody character with additional cedar-like facets for more natural effects.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards

RIFM Assessment

No specific RIFM assessment found for this material.

Sustainability

As a synthetic material, this compound avoids the environmental impact of harvesting natural materials. However, its production requires petrochemical feedstocks and energy-intensive processes. The fragrance industry is increasingly evaluating such materials for greener synthesis routes while maintaining their performance benefits in sustainable fragrance design.

Explore 6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-7-(1-methylethyl)-

Browse essential oils and aroma compounds.

Browse on iHerb →

Affiliate disclosure: we may earn a small commission at no extra cost to you.

References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

    Report a data error

    Similar Posts