Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- (CAS 16485-10-2) — Woody Middle Note Fragrance Ingredient

Woody · Floral

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-

CAS 16485-10-2

Origin
synthetic
Note
Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-?

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- is a synthetic fragrance ingredient used in fine perfumery. It contributes to the complexity and longevity of fragrances. This compound is valued for its ability to enhance floral and woody notes, making it a versatile tool for perfumers.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Use with awareness
CAS
16485-10-2
Formula
Mixture
MW
Variable
Odor Family
Woody · Floral
Layer 1 · Enthusiast

What Does Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- Smell Like?

This synthetic molecule offers a subtle, yet complex olfactory profile. It starts with a faintly floral and slightly woody character, evolving into a more pronounced heart note with hints of green and sweet undertones. The dry-down reveals a soft, balsamic warmth that lingers delicately on the skin.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- is a synthetic compound belonging to the amide class. It is not found in nature and is synthesized through specific chemical reactions. Its structure includes multiple hydroxyl groups, contributing to its solubility and reactivity in fragrance formulations.

Physical & Chemical Properties

Boiling PointN/A
DensityN/A

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 10%Enhances floral and woody accords

Classic Accords

Tip: Use in small amounts to add depth to floral and woody compositions.

Alternatives & Comparisons

1
Vanillin CAS 121-33-5

A more common alternative for sweet, vanilla-like notes in fragrances.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not restricted by IFRA.

RIFM Assessment

No specific RIFM safety assessment found.

Sustainability

As a synthetic compound, its environmental impact depends on manufacturing processes. Sustainable synthesis methods are encouraged to minimize ecological footprint.

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References

  1. PubChem. Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-. PubChem

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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