6-Nonenal, (6E)- (CAS 2277-20-5) — Green Top Note Fragrance Ingredient
6-_Nonenal, (6E)_-
CAS 2277-20-5
What Is 6-_Nonenal, (6E)_-?
6-Nonenal is a synthetic compound used in perfumery to create green, cucumber-like, and fatty notes. It’s often found in fragrances aiming for aquatic or fresh vegetable effects. This aldehyde is powerful at low concentrations, contributing to modern, ozonic scent profiles. Its unique aroma makes it valuable for creating cutting-edge perfumes that break from traditional floral or woody themes.
Safety Profile
USE WITH AWARENESSWhat Does 6-_Nonenal, (6E)_- Smell Like?
6-Nonenal delivers a sharp, green burst reminiscent of freshly cut cucumbers and watermelon rind, with an underlying fatty, slightly metallic edge. As it evolves, the fatty character becomes more pronounced, akin to the oiliness of crushed leaves, while retaining a watery freshness. The dry-down reveals a subtle, lingering greenness that blends seamlessly with woody and musky bases.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used to enhance the aquatic, fresh cucumber facet that defines this iconic fragrance, contributing to its modern, watery transparency.
Adds a crisp, green vegetal note that complements the mango and grapefruit, creating a vivid garden effect.
Chemistry, Properties & Perfumer Guide
The Chemistry
6-Nonenal is an unsaturated aldehyde with the formula C9H16O. It belongs to the class of nonenals, which are known for their potent green and fatty odors. The compound is typically synthesized through the oxidation of corresponding alcohols or via hydroformylation of unsaturated hydrocarbons. Its (E)-isomer is particularly significant in perfumery due to its intense aroma.
Physical & Chemical Properties
| Boiling Point | 198 °C |
|---|---|
| Density | 0.865 g/cm³ |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.1-0.5% | Up to 1% | Used for fresh, green top notes |
| Functional Fragrances | 0.05-0.2% | Up to 0.5% | Adds freshness to detergents and cleaners |
Classic Accords
Tip: Use sparingly to avoid overpowering other notes; blends well with citrus and ozonic molecules.
Alternatives & Comparisons
More intense cucumber note, used when a stronger green character is desired.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No IFRA restrictions currently apply to 6-Nonenal.
EU Allergen Declaration
Not listed as an EU allergen.
GHS Classification
RIFM Assessment
RIFM has assessed 6-Nonenal as safe for use in current fragrance applications at typical levels.
Sustainability
6-Nonenal is synthesized from petrochemical sources, with no known natural occurrence. Its production is energy-intensive but requires minimal quantities due to its potency. Future green chemistry approaches may offer more sustainable synthesis routes.
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References
- PubChem Compound Summary for 6-Nonenal PubChem
- Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
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