Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc (CAS 13144-88-2) — Mid Note Fragrance Ingredient

ByThe Good Scents



terpenic

Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc

CAS 13144-88-2

Note
mid
Volatility
medium
MW
180.3
Data as of: Jun 2026

What Is Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc?

Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc (CAS 13144-88-2) is an aroma chemical used as a fragrance and flavour ingredient. Its odour is described as floral, fruity and honey, placing it within the terpenic family as a mid note with medium volatility. With a molecular weight of 180.3 (formula C12H20O), it is handled by perfumers as a building block for compositions where a floral character is desired. The data below is compiled from public chemical and regulatory sources.

Safety Profile

USE WITH AWARENESS

Generally safeUse with awarenessProfessional use
CAS
13144-88-2
Formula
C12H20O
MW
180.3
InChIKey
LLCMOZBDJDCWLT-UHFFFAOYSA-N
Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc 2D structure

Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc
C12H20O
Layer 1 · Enthusiast

What Does Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc Smell Like?

The odour profile of Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc is reported as floral, fruity, honey, plum, rose, tobacco. The dominant facet is its floral character, with the remaining notes adding nuance and complexity. As a mid note it contributes to the heart of a fragrance. Perceived intensity and exact character depend on concentration, the carrier and the surrounding accord.

Scent Profile

Profile derived from public odour-descriptor data; relative, not absolute.

Layer 2

Chemistry & Properties

The Chemistry

Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc has the molecular formula C12H20O and a molecular weight of 180.3 g/mol. Its canonical SMILES representation is CC1=C(C(C(C1)(C)C)(C)C)C(=O)C. Its reported log P (XLogP) of 2.80 indicates a lipophilic, oil-soluble molecule, which informs how it partitions in a formula. Physical constants below are drawn from PubChem and EPA CompTox public datasets.

Physical & Chemical Properties

Molecular Weight 180.3 g/mol
Boiling Point 232.3 °C
Melting Point 39.23 °C
Flash Point 86.07 °C
Density 0.8263 g/cm³
Vapor Pressure 0.1028 mmHg
Water Solubility 0.002512 g/L
XLogP 2.80

Perfumer Guide

Note Position
Mid
Volatility
Medium
Primary Odour
Floral

Alternatives & Comparisons

Ingredients occupying a similar odour space — useful as substitutes or companions when Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc is unavailable or restricted.

1
1-(2,4,4-Trimethyl-1-cyclohexen-1-yl)-2-buten-1-one CAS 70266-48-7

Shares floral, fruity, honey character — a candidate substitute or companion in the same odour space.

2
4-(2,6,6-Trimethylcyclohex-1-Enyl)But-2-En-4-One CAS 35044-68-9

Shares fruity, floral, black character — a candidate substitute or companion in the same odour space.

3
1-(2,6,6-trimethylcyclohex-3-en-1-yl)but-2-en-1-one CAS 71048-82-3

Shares apple, floral, fruity character — a candidate substitute or companion in the same odour space.

Layer 3

Safety & Regulatory

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH and EU Cosmetics Regulation standards update periodically. Consult the current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

Subject to an IFRA restriction (51st Amendment) — maximum use levels apply by product category. Consult the current IFRA Standards Library before formulating.

GHS Classification

Signal word: Warning

H317
Formulating with Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc?

Open Ethanone, 1-(2,4,4,5,5-pentamethyl-1-cyc in Fragrance Studio (Pro) for the calibrated vapour-pressure curve, the modelled odour-threshold estimate, and the substitute-matching engine across 2,900+ aromachemicals.

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References & Sources

  1. PubChem Compound Summary (NIH) — search by InChIKey
  2. EPA CompTox Chemicals Dashboard — physicochemical & fate data
  3. IFRA Standards Library (49th / 51st Amendment)
Sources: PubChem (NIH) · EPA CompTox · IFRA Standards Library · public GHS classification. Odour descriptors are original editorial summaries of public profiles, not reproduced from any single proprietary source.

Data: PubChem (NIH), EPA CompTox, IFRA. Last reviewed: Jun 2026.

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