8H-Indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl Mixture of isomers (CAS 338735-71-0) — Woody Base Note Fragrance Ingredient
8H-Indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl Mixture of isomers
CAS 338735-71-0
What Is 8H-Indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl Mixture of isomers?
This synthetic fragrance ingredient is a complex mixture of isomers used primarily in modern perfumery to create unique woody-ambery effects. It’s found in niche fragrances where avant-garde scent profiles are desired. The material offers perfumers a sophisticated alternative to traditional ambery materials, contributing to long-lasting dry-down effects in contemporary compositions.
Safety Profile
USE WITH AWARENESSWhat Does 8H-Indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl Mixture of isomers Smell Like?
This complex synthetic presents a multifaceted woody-ambergris character with subtle animalic undertones. Initially, it offers a clean, slightly metallic top note that evolves into a warm, slightly sweet heart reminiscent of sun-bleached driftwood. The dry-down reveals a sophisticated amber-like richness with hints of dry leather and faint tobacco, creating exceptional tenacity on skin. The material behaves like an olfactory chameleon, amplifying woody elements while adding depth to oriental accords.
2D Molecular Structure
SMILES: CC1CC2CCC3C(C2O1)C(C)(C)C(C)C3(C)C
Chemistry, Properties & Perfumer Guide
The Chemistry
This synthetic belongs to the polycyclic furan class, specifically a decahydro indeno-furan derivative with six methyl groups creating multiple stereoisomers. The material is produced through complex Diels-Alder reactions followed by hydrogenation and methylation steps. The mixture of isomers contributes to its multifaceted odor profile, with each isomer imparting different facets to the overall scent. The rigid polycyclic structure provides excellent stability and longevity in fragrance formulations.
Physical & Chemical Properties
| Appearance | Colorless to pale yellow liquid |
|---|---|
| Odor Strength | Medium to high |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-2% | Up to 5% | Amber base note enhancer |
| Home Care | 0.1-0.5% | Up to 1% | Long-lasting woody note |
Classic Accords
Tip: Use in trace amounts to add depth without overpowering; excellent for modern chypre reconstructions.
Alternatives & Comparisons
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not currently restricted by IFRA. Listed on IFRA Transparency List.
RIFM Assessment
Under evaluation by RIFM. Preliminary data suggests safe use at current industry levels.
Sustainability
As a synthetic material, this ingredient avoids natural resource depletion concerns. The manufacturing process employs standard petrochemical feedstocks with standard industry controls. While not biodegradable, its low usage levels in formulations minimize environmental impact. The material’s potency reduces the carbon footprint per unit of fragrance effect compared to some natural alternatives.
Explore 8H-Indeno(4,5-B)furan,2,3,3a,4,5,5a,6,7,8a,9-decahydro-2,6,6,7,8,8-hexamethyl Mixture of isomers
Browse essential oils and aroma compounds.
Browse on iHerb →Affiliate disclosure: we may earn a small commission at no extra cost to you.
References
- IFRA Transparency List IFRA Website
- Patent literature on polycyclic furans Google Patents
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data errorIngredient Data Sheet
CAS 338735-71-0Physical Properties
| Molecular Weight | 250.4 g/mol🔬 PubChem |
| LogP (Octanol-Water) | 5.1🔬 PubChem |
| log Kp (skin permeability) | -0.606💻 Calculated |
| SMILES | CC1CC2CCC3C(C2O1)C(C(C3(C)C)C)(C)C🔬 PubChem |
Odor & Flavor
| Functional Groups | ether💻 RDKit |
Regulatory Status
| IFRA Listed | Yes — see IFRA Standards for category limits⚖️ IFRA 51 |
Trade Names
| Trisamber®(IFF; the commercial quality contains some noncyc-📖 Surburg |
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.
Physicochemical Properties
DTXSID: DTXSID9051373
Physical Properties
| Molecular Weight | 250.426 g/mol🔬 EPA CompTox |
| Density | 0.893 g/cm^3📊 OPERA |
| Boiling Point | 287.538 °C📊 OPERA |
| Melting Point | 83.972 °C📊 OPERA |
| Flash Point | 121.056 °C📊 OPERA |
| Refractive Index | 1.453 Dimensionless📊 OPERA |
| Molar Volume | 282.779 cm^3/mol📊 OPERA |
Partition & Solubility
| LogP (Octanol-Water) | 5.822 Log10 unitless📊 OPERA |
| LogD (pH 5.5) | 5.822 Log10 unitless📊 OPERA |
| LogD (pH 7.4) | 5.822 Log10 unitless📊 OPERA |
| LogKoa (Octanol-Air) | 7.42 Log10 unitless📊 OPERA |
| Water Solubility | 0 mol/L📊 OPERA |
| Henry's Law Constant | 0.001 atm-m3/mole📊 OPERA |
Transport Properties
| Vapor Pressure | 0.002 mmHg📊 OPERA |
| Viscosity | 11.3 cP📊 OPERA |
| Surface Tension | 27.448 dyn/cm📊 OPERA |
| Thermal Conductivity | 88.143 mW/(m*K)📊 OPERA |
Molecular Descriptors
| Topological Polar Surface Area | 9.23 Ų💻 Computed |
| H-Bond Donors | 0 count💻 Computed |
| H-Bond Acceptors | 1 count💻 Computed |
| Rotatable Bonds | 0 count💻 Computed |
| Aromatic Rings | 0 count💻 Computed |
| Molar Refractivity | 76.498 cm^3/mol📊 OPERA |
| Polarizability | 30.326 Å^3📊 OPERA |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
Related Research
![4,7,7-Trimethyl-2-(3-methyl-2-butenyl)bicyclo[4.1.0]heptan-3-one (CAS 74499-58-4) — Woody Base Note Fragrance Ingredient](https://thegoodscents.company/wp-content/uploads/2026/04/4-7-7-trimethyl-2-1-1-768x439.webp)
![Ethanone, 1-(2,3-dimethylbicyclo[2.2.1]hept-2-yl)- (CAS 854737-10-3) — Woody Middle Note Fragrance Ingredient](https://thegoodscents.company/wp-content/uploads/2026/04/ethanone-1-1-15-768x439.webp)
![9,10-Anthracenedione, 1-amino-2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]-4-[(2,4,6-trimethylphenyl)amino]- (CAS 71701-33-2) — Citrus Not applicable Note Fragrance Ingredient](https://thegoodscents.company/wp-content/uploads/2026/04/9-10-anthracenedione-1-amino-2-4-1-1-768x439.webp)