Benzene, 1,3,5-trimethyl- (CAS 108-67-8) — Woody N/A Note Fragrance Ingredient
Benzene, 1,3,5-trimethyl-
CAS 108-67-8
What Is Benzene, 1,3,5-trimethyl-?
1,3,5-Trimethylbenzene (mesitylene) is a synthetic aromatic hydrocarbon used in industrial solvents and chemical synthesis. Consumers may encounter it in trace amounts as a byproduct in some petroleum-derived products. While not commonly used in perfumery, its volatility makes it relevant for studying fragrance behavior. Understanding such compounds helps perfumers avoid unwanted chemical interactions and ensures product stability.
Safety Profile
PROFESSIONAL USEWhat Does Benzene, 1,3,5-trimethyl- Smell Like?
Mesitylene presents a sharp, gasoline-like aromatic odor with dry, rubbery undertones. The initial blast is intensely chemical – reminiscent of solvent markers or fresh asphalt. As it evaporates, the harshness mellows into a flat, metallic dryness without any sweetness. Unlike more complex aromatics, it lacks evolution, maintaining a linear industrial character throughout its duration.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Chemistry, Properties & Perfumer Guide
The Chemistry
Mesitylene is a trimethyl-substituted benzene derivative belonging to the C9 aromatic hydrocarbon family. Industrially produced via methylation of toluene or xylene, it serves primarily as a solvent and chemical intermediate rather than a fragrance ingredient. The symmetric 1,3,5 substitution pattern creates a stable, electron-rich aromatic system with limited reactivity compared to other alkylbenzenes.
Physical & Chemical Properties
| Boiling Point | 164-165 °C |
|---|---|
| Density | 0.865 g/cm³ (20°C) |
| Flash Point | 44 °C |
| Vapor Pressure | 2.3 mmHg (20°C) |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Industrial | 0% | N/A | Not for fragrance applications |
Classic Accords
Tip: Not recommended for perfumery due to toxicity concerns.
Alternatives & Comparisons
Safer aromatic hydrocarbon with citrus-herbaceous notes, used as a solvent carrier in fragrances.
Higher-boiling aromatic with less sharp odor profile, occasionally used in functional perfumery.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not listed by IFRA – industrial chemical outside fragrance scope.
GHS Classification
RIFM Assessment
No RIFM assessment – not a fragrance material.
Sustainability
Petroleum-derived synthetic with significant carbon footprint. No known natural sources. Industrial production involves energy-intensive processes with potential VOC emissions. Not considered sustainable for perfumery applications.
Explore Benzene, 1,3,5-trimethyl-
Browse essential oils and aroma compounds.
Browse on iHerb →Affiliate disclosure: we may earn a small commission at no extra cost to you.
References
- PubChem Compound Summary for CID 7949 PubChem
- European Chemicals Agency (ECHA) Substance Information ECHA
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data error
![endo-1,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-ol (CAS 28462-85-3) — Woody Middle to base Note Fragrance Ingredient](https://thegoodscents.company/wp-content/uploads/2026/04/endo-1-2-3-3-tetramethylbicyclo-2-2-1-heptan-2-ol-1-768x439.webp)
