Benzoic acid, 2-((3-(1,3-benzodioxol-5-yl)-2-methylpropylidene)amino)-, methyl ester (CAS 111753-60-7) — Spicy Unknown Note Fragrance Ingredient

Spicy · Balsamic

Benzoic acid, 2-((3-(1,3-benzodioxol-5-yl)-2-methylpropylidene)amino)-, methyl ester

CAS 111753-60-7

Origin
synthetic
Note
Unknown
IFRA
Use with awareness
Data as of: Apr 2026

What Is Benzoic acid, 2-((3-(1,3-benzodioxol-5-yl)-2-methylpropylidene)amino)-, methyl ester?

This synthetic fragrance compound is rarely encountered by consumers directly, but may appear in niche perfumes as a specialty ingredient. It belongs to a class of aromatic chemicals designed to create unique olfactory effects. While not widely used, such ingredients allow perfumers to craft distinctive scent signatures that stand out in luxury and artistic fragrance compositions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Limited safety data available
Potential skin sensitizer – patch test recommended
CAS
111753-60-7
Formula
Mixture
MW
Variable
Odor Family
Spicy · Balsamic
Layer 1 · Enthusiast

What Does Benzoic acid, 2-((3-(1,3-benzodioxol-5-yl)-2-methylpropylidene)amino)-, methyl ester Smell Like?

No specific odor profile available for this rare synthetic compound. Based on its chemical structure, it may exhibit complex aromatic characteristics with potential spicy, woody, or balsamic nuances. The benzodioxole moiety suggests possible herbal or anisic facets, while the ester group could contribute subtle fruity undertones. Performance would depend heavily on concentration and blending with other materials.

Scent Profile
Layer 2

2D Molecular Structure

Methyl 2-{[3-(2H-1,3-benzodioxol-5-yl)-2-methylpropylidene]amino}benzoate

SMILES: COC(=O)C1=CC=CC=C1N=CC(C)CC1=CC2=C(OCO2)C=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

This specialized synthetic molecule features a benzodioxole aromatic system connected to a methylpropylideneamino benzoate ester structure. The 1,3-benzodioxole moiety is notable for its presence in natural compounds like safrole. Synthesis would likely involve multi-step reactions including esterification and condensation steps. The methylene bridge and ester group create potential sites for metabolic breakdown.

Physical & Chemical Properties

Perfumer Guide

Note Position
Unknown
Volatility
Unknown
Blending
Unknown
ApplicationTypical %RangeNotes

Classic Accords

Tip: Conduct small-scale trials to assess odor profile and blending behavior before large-scale use.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions found for this material.

RIFM Assessment

No RIFM assessment data available for this compound.

Sustainability

As a synthetic material, production would involve petrochemical feedstocks and organic synthesis processes. Environmental impact depends on manufacturing practices and waste management. Being a specialty chemical, production volumes are likely small with limited ecological footprint compared to high-volume fragrance ingredients.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Physicochemical Properties

    DTXSID: DTXSID60869413

    Physical Properties

    Molecular Weight 325.364 g/mol🔬 EPA CompTox
    Density 1.215 g/cm^3📊 OPERA
    Boiling Point 426.857 °C📊 OPERA
    Melting Point 99.947 °C📊 OPERA
    Flash Point 208.091 °C📊 OPERA
    Refractive Index 1.576 Dimensionless📊 OPERA
    Molar Volume 272.617 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 3.831 Log10 unitless📊 OPERA
    LogD (pH 5.5) 3.816 Log10 unitless📊 OPERA
    LogD (pH 7.4) 3.806 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 10.18 Log10 unitless📊 OPERA
    Water Solubility 0 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0 mmHg📊 OPERA
    Surface Tension 41.383 dyn/cm📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 57.12 Ų💻 Computed
    H-Bond Donors 0 count💻 Computed
    H-Bond Acceptors 5 count💻 Computed
    Rotatable Bonds 5 count💻 Computed
    Aromatic Rings 2 count💻 Computed
    Molar Refractivity 90.166 cm^3/mol📊 OPERA
    Polarizability 35.745 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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