Butane, 1,1′-[methylenebis(oxy)]bis- (CAS 2568-90-3) — Woody Middle Note Fragrance Ingredient

Woody · Green

Butane, 1,1'-[methylenebis(oxy)]bis-

CAS 2568-90-3

Origin
synthetic
Note
Middle
IFRA
Professional use
Data as of: Apr 2026

What Is Butane, 1,1'-[methylenebis(oxy)]bis-?

This synthetic compound is a specialized fragrance ingredient primarily used in industrial applications and some niche perfumery. Consumers might encounter it in certain modern fragrances where its unique chemical structure contributes to novel scent profiles. While not a household name, it represents how modern chemistry expands perfumers’ palettes with innovative materials that don’t exist in nature.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Limited safety data available
Requires professional handling
CAS
2568-90-3
Formula
Mixture
MW
Variable
Odor Family
Woody · Green
Layer 1 · Enthusiast

What Does Butane, 1,1'-[methylenebis(oxy)]bis- Smell Like?

This synthetic molecule presents a clean, ethereal character with subtle metallic undertones. Its odor profile evolves from an initial sharp, almost ozone-like top note to a more subdued, waxy heart. The dry-down reveals faint woody-amber nuances, though the overall impression remains quite transparent. The scent lingers close to the skin with remarkable persistence for such a lightweight molecule, creating an intriguing contrast between its ephemeral quality and lasting presence.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

This synthetic compound belongs to the class of ethers, characterized by its methylenebis(oxy) functional group bridging two butane chains. While not found in nature, its structure suggests potential as a fragrance modifier. The synthesis typically involves etherification reactions under controlled conditions. The symmetrical nature of the molecule contributes to its stability and distinctive olfactory properties.

Physical & Chemical Properties

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-6 hours)
Blending
Fair
ApplicationTypical %RangeNotes
Industrial Fragrance0.5-2%Up to 5%Used for novel effects
Niche Perfumery0.1-1%Up to 3%Experimental applications

Classic Accords

Tip: Use sparingly in experimental compositions seeking unconventional metallic-waxy effects.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards.

RIFM Assessment

No RIFM assessment currently available for this material.

Sustainability

As a purely synthetic material, this compound avoids natural resource depletion but requires energy-intensive production. Its environmental impact depends on manufacturing processes and disposal methods. The lack of biodegradability data suggests caution in formulation.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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