Cyclohexane, 1,1-[oxybis(methylene)]bis- (CAS 14315-63-0) — Woody Middle Note Fragrance Ingredient

Woody · Green

Cyclohexane, 1,1_-[oxybis(methylene)]bis-

CAS 14315-63-0

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is Cyclohexane, 1,1_-[oxybis(methylene)]bis-?

This synthetic compound is a specialized fragrance ingredient primarily encountered in modern perfumery. It contributes to complex scent structures in niche and avant-garde fragrances. While not widely recognized by name, it plays a subtle role in creating depth and longevity in contemporary scent compositions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Approved for fragrance use
Limited safety data available
CAS
14315-63-0
Formula
Mixture
MW
Variable
Odor Family
Woody · Green
Layer 1 · Enthusiast

What Does Cyclohexane, 1,1_-[oxybis(methylene)]bis- Smell Like?

This synthetic molecule presents a clean, slightly woody character with subtle ozonic undertones. The initial impression is crisp and modern, evolving into a faintly metallic heart that adds structural complexity. In dry-down, it contributes a barely perceptible warmth that helps anchor brighter top notes without overwhelming them.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

This bicyclic ether belongs to the class of oxygen-containing cyclohexane derivatives. Synthesized through etherification reactions, its rigid molecular structure contributes to moderate volatility. The oxygen bridge creates polarity while the cyclohexane rings provide hydrophobic character, making it useful for bridging polar and non-polar fragrance components.

Physical & Chemical Properties

Perfumer Guide

Note Position
Middle
Volatility
Moderate (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Used as structural element

Classic Accords

Tip: Use sparingly to add backbone to fresh-modern accords without dominating.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions currently apply.

RIFM Assessment

Limited safety assessment data available.

Sustainability

As a synthetic material, production avoids natural resource depletion but requires petrochemical feedstocks. Future green chemistry approaches may offer more sustainable synthesis routes.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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