Cinnamyl formate (CAS 104-65-4) — Spicy Middle Note Fragrance Ingredient

Spicy · Sweet

Cinnamyl formate

CAS 104-65-4

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is Cinnamyl formate?

Cinnamyl formate is a synthetic fragrance compound that mimics the warm, spicy-sweet aroma of cinnamon. It’s commonly found in perfumes, candles, and flavored products. This ingredient adds depth and warmth to fragrance compositions, creating a cozy, inviting atmosphere.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Approved for use in cosmetics
Potential skin sensitizer at high concentrations
CAS
104-65-4
Formula
Mixture
MW
Variable
Odor Family
Spicy · Sweet
Layer 1 · Enthusiast

What Does Cinnamyl formate Smell Like?

Cinnamyl formate bursts with an intense, spicy-sweet cinnamon character, reminiscent of freshly baked goods. The top note is sharp and slightly fruity, evolving into a heart of warm, balsamic richness. As it dries down, it reveals a soft, vanillic sweetness that lingers on the skin. The overall effect is like a gourmand cinnamon roll with a sophisticated edge – comforting yet elegant.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Spicebomb(Viktor&Rolf, 2012)

Used as a spicy accent that complements the fragrance’s explosive cinnamon and saffron heart, adding warmth and diffusion to this modern masculine gourmand.

Angel(Mugler, 1992)

Provides a spicy counterpoint to the chocolate-patchouli base, creating tension between sweet and spicy elements in this iconic gourmand oriental.

Layer 2

2D Molecular Structure

Cinnamyl formate

SMILES: O=COCC=CC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

Cinnamyl formate is an ester formed from cinnamyl alcohol and formic acid. As a synthetic molecule, it’s typically produced through esterification reactions under acidic conditions. The compound features both an aromatic phenyl group and an ester functional group, which combine to produce its characteristic warm-spicy odor profile. Its molecular structure allows for good stability in various product formulations.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
Odor StrengthMedium to strong

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Used as spicy modifier
Home Fragrance1-3%Up to 8%Adds warmth to candle scents

Classic Accords

+ Vanilla + Benzoin = Gourmand + Clove + Orange = Christmas spice

Tip: Use in trace amounts to add warmth to floral compositions without overpowering delicate notes.

Alternatives & Comparisons

1
Cinnamyl acetate CAS 103-54-8

Offers similar cinnamon character but with a fruitier, less sharp profile. Better for softer applications where a rounded spice is desired.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently apply to cinnamyl formate (as of 2023).

EU Allergen Declaration

Not listed as an EU allergen.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

RIFM has evaluated cinnamyl formate and found it safe for current usage levels in fragrance applications.

Sustainability

As a synthetic material, cinnamyl formate doesn’t rely on agricultural production. Its synthesis can be optimized for minimal environmental impact through green chemistry principles. Being produced in controlled facilities reduces variability compared to natural cinnamon derivatives.

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References

  1. Bauer, K. et al. (2001). Common Fragrance and Flavor Materials. Wiley-VCH.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 104-65-4

Physical Properties

Molecular Weight162.18 g/mol🔬 PubChem
LogP (Octanol-Water)2.5🔬 PubChem
Boiling Point250 °C🔬 EPA CompTox
Vapor Pressure0.011 mmHg @ 25°C📊 OPERA
Flash Point100 °C🔬 EPA CompTox
Involatility Index0.0009💻 Calculated
log Kp (skin permeability)-1.914💻 Calculated
SMILESC1=CC=C(C=C1)C=CCOC=O🔬 PubChem

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassVery slow💻 Calculated
Persistence Score3.2 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsapplebalsamicfruityherbal• leffingwell
Functional Groupsetheralkenearomatic💻 RDKit
“Green-herbaceous, yet "cinnamic" odor, balsamic, but more "dry"-fruity than the higher cinnamates. Powerful and of good tenacity.”📖 Arctander
Cinnamyl formate has a balsamic, fruital-floral odor and bittersweet taste reminiscent of apple.📖 Fenaroli

Flavor Notes (Arctander)

“Used in trace amounts in flavor compositions, particularly Apple, Banana, Cherry, Pear, Spice, etc.”📖 Arctander

Regulatory Status

FEMA NumberFEMA 2299⚖️ FEMA GRAS
GRAS StatusGenerally Recognized as Safe⚖️ FEMA GRAS
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID00861714

Physical Properties

Molecular Weight 162.188 g/mol🔬 EPA CompTox
Density 1.08 g/cm^3🔬 EPA CTX
Boiling Point 251.333 °C🔬 EPA CTX
Melting Point 0 °C🔬 EPA CTX
Flash Point 118.533 °C🔬 EPA CTX
Refractive Index 1.56 Dimensionless📊 OPERA
Molar Volume 150.597 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 2.275 Log10 unitless📊 OPERA
LogD (pH 5.5) 2.275 Log10 unitless📊 OPERA
LogD (pH 7.4) 2.275 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.2 Log10 unitless📊 OPERA
Water Solubility 0.003 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.475 mmHg📊 OPERA
Viscosity 2.707 cP📊 OPERA
Surface Tension 39.079 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 26.3 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 2 count💻 Computed
Rotatable Bonds 4 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 48.707 cm^3/mol📊 OPERA
Polarizability 19.309 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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