2-Undecanone (CAS 0112-12-9) — Musky Middle Note Fragrance Ingredient

Musky · Green

2-Undecanone

CAS 0112-12-9

Origin
synthetic
Note
Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is 2-Undecanone?

2-Undecanone is a synthetic fragrance ingredient with a waxy, fruity-musky odor. It’s found in some perfumes and functional fragrances like detergents. This molecule matters because it provides a clean, diffusive musk note that blends well with both floral and citrus accords.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major restrictions
Moderate skin sensitivity potential
CAS
0112-12-9
Formula
Mixture
MW
Variable
Odor Family
Musky · Green
Layer 1 · Enthusiast

What Does 2-Undecanone Smell Like?

2-Undecanone opens with a crisp, waxy-green character reminiscent of freshly cut cucumber skins. As it evolves, a subtle fruity undertone emerges – think underripe bananas with a hint of melon rind. The dry-down reveals its true nature: a clean musk that lingers close to the skin with excellent diffusion. Unlike animalic musks, this maintains a bright, almost citrusy quality that prevents heaviness.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Undecanone is a methyl ketone with an 11-carbon chain. While trace amounts occur naturally in some foods, commercial production is entirely synthetic via oxidation of 2-undecanol or Friedel-Crafts acylation. The molecule’s linear structure gives it excellent stability in alkaline formulations. Its relatively low molecular weight contributes to good volatility as a top-to-middle note.

Physical & Chemical Properties

Boiling Point228-230 °C
Density0.825 g/cm³
Flash Point96 °C

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Musky modifier
Functional Fragrances0.5-2%Up to 3%Diffusive freshness

Classic Accords

Tip: Use to add diffusion to citrus colognes without animalic undertones.

Alternatives & Comparisons

1
Muscone CAS 541-91-3

More expensive but provides a richer musk character for luxury applications.

2
Habanolide CAS 105-95-3

Macrocyclic musk with better longevity but less diffusion.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not restricted under current IFRA standards.

GHS Classification

H315 Skin irritation

RIFM Assessment

RIFM assessment confirms safe use at current industry levels.

Sustainability

As a synthetic material, 2-Undecanone avoids natural resource depletion concerns. Production typically uses petrochemical feedstocks, though bio-based routes are being explored. Its efficiency at low usage levels makes it relatively sustainable compared to some natural musks.

Explore 2-Undecanone

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References

  1. Bauer et al. (2001). Common Fragrance and Flavor Materials. Wiley-VCH.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 0112-12-9

Physical Properties

Molecular Weight170.29 g/mol🔬 PubChem
LogP (Octanol-Water)4.1🔬 PubChem
log Kp (skin permeability)-0.828💻 Calculated

Odor & Flavor

Primary Descriptorscitrusfatty• leffingwell
“herbaceous fragrance types, in herbal-spicy beta-Oxoundecane. Fruity-rosy, Orange-like odor, slightly her- G.R.A.S. Oily-fruity, also herbaceous taste with a 2) from Decanoic acid and Acetic acid, heat- slightly Coconut-like note.”📖 Arctander

Sensory Thresholds

Odor Detection Threshold0.1453 ppm (n=5)📖 van Gemert
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

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