Cyclohexanone, 2-methyl-5-(1-methylethyl)- (CAS 59471-80-6) — Woody Middle Note Fragrance Ingredient
Cyclohexanone, 2-_methyl-_5-_(1-_methylethyl)_-
CAS 59471-80-6
What Is Cyclohexanone, 2-_methyl-_5-_(1-_methylethyl)_-?
Cyclohexanone, 2-methyl-5-(1-methylethyl)- is a synthetic fragrance compound used in perfumery for its woody, camphoraceous scent. While not commonly recognized by name, it appears in many woody and fougère fragrances. This ingredient matters as a versatile synthetic that provides depth and diffusion to fragrance compositions, often enhancing more expensive natural materials.
Safety Profile
GENERALLY SAFEWhat Does Cyclohexanone, 2-_methyl-_5-_(1-_methylethyl)_- Smell Like?
This synthetic ketone delivers a crisp, woody-camphoraceous profile with subtle minty undertones. The initial impact is fresh and slightly medicinal, reminiscent of crushed eucalyptus leaves, which gradually settles into a dry woody character with faintly sweet, resinous nuances. In dry-down, it behaves like a light patchouli alternative, providing excellent diffusion without overwhelming floral or citrus notes in the heart.
Chemistry, Properties & Perfumer Guide
The Chemistry
A substituted cyclohexanone derivative belonging to the alicyclic ketone class. Synthesized through Friedel-Crafts acylation of isopropylbenzene derivatives followed by hydrogenation. The methyl and isopropyl substitutions create steric hindrance that influences both volatility and odor characteristics. No known natural occurrence – exclusively produced through organic synthesis routes.
Physical & Chemical Properties
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 1-3% | Up to 5% | Woody modifier |
| Functional Fragrance | 0.5-2% | Up to 3% | Diffusion booster |
Classic Accords
Tip: Use to add lift to heavy woody bases without adding sweetness.
Alternatives & Comparisons
When a less camphoraceous, more ambery wood note is desired with similar stability profile.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not currently restricted by IFRA standards.
RIFM Assessment
No specific RIFM assessment found for this specific isomer.
Sustainability
As a purely synthetic material, production relies on petrochemical feedstocks. The multi-step synthesis requires energy-intensive processes but avoids agricultural land use. No known biodegradation studies available for this specific compound.
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