Dimethyl phthalate (CAS 0131-11-3) — Sweet Base Note Fragrance Ingredient

Sweet · Citrus

Dimethyl phthalate

CAS 0131-11-3

Origin
synthetic
Note
Base
IFRA
Use with awareness
Data as of: Apr 2026

What Is Dimethyl phthalate?

Dimethyl phthalate is a synthetic fragrance ingredient primarily used as a solvent and fixative in perfumes and cosmetic products. Consumers may encounter it in long-lasting fragrances, hair sprays, and some personal care items. While not a dominant scent itself, it plays a crucial technical role by helping other fragrance notes last longer on the skin. Its ability to slow evaporation makes it valuable for creating perfumes with good longevity.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
IFRA restricted due to sensitization potential
EU-regulated as potential endocrine disruptor
CAS
0131-11-3
Formula
Mixture
MW
Variable
Odor Family
Sweet · Citrus
Layer 1 · Enthusiast

What Does Dimethyl phthalate Smell Like?

Dimethyl phthalate is nearly odorless when pure, presenting only a faint, slightly sweet chemical character. In formulations, it acts as a quiet workhorse rather than a featured note, subtly rounding out sharper fragrance components. Its primary value lies in its physical properties – it forms an invisible scaffold that extends the life of more volatile top notes while adding minimal olfactory interference. The dry-down is neutral, allowing the true character of the fragrance composition to shine through without distortion.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Shalimar(Guerlain, 1925)

Used as a fixative to stabilize the vanilla-oriental accord, allowing the complex blend to maintain balance through extended wear.

Chanel No. 5(Chanel, 1921)

Historically employed to prolong the legendary aldehydic floral bouquet, though modern formulations have phased it out.

Opium(Yves Saint Laurent, 1977)

Helped anchor the intense spice and amber notes in this oriental classic before reformulation.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Dimethyl phthalate is an ester formed from phthalic acid and methanol. As the simplest phthalate ester, it belongs to a class of compounds widely used as plasticizers and solvents. Industrially produced via esterification of phthalic anhydride with methanol in the presence of acid catalysts, this colorless liquid exhibits excellent solvency for many organic compounds. Its molecular structure features two ester groups on a benzene ring, creating polarity that contributes to its fixative properties while remaining sufficiently volatile for fragrance applications.

Physical & Chemical Properties

Boiling Point283-285 °C
Density1.19 g/cm³
Flash Point146 °C
Vapor Pressure0.01 mmHg at 25°C

Perfumer Guide

Note Position
Base
Volatility
Very low (hours-days)
Blending
Technical
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Restricted by IFRA
Hair Care0.1-0.5%Up to 1%Mainly in hair sprays
Functional Products0.01-0.1%Trace amountsAs solvent/fixative

Classic Accords

+ Vanilla + Musk = Oriental fixative + Citrus Oils = Long-lasting cologne

Tip: Use minimal amounts as needed for fixation – start at 0.5% and evaluate longevity.

Alternatives & Comparisons

1
Diethyl phthalate CAS 84-66-2

Similar fixative properties with slightly lower volatility and reduced regulatory concerns.

2
Benzyl benzoate CAS 120-51-4

Natural alternative with fixative properties and a mild balsamic note.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Restricted under IFRA 49th Amendment (2019) to 0.5% in leave-on products due to sensitization potential.

EU Allergen Declaration

Not classified as EU allergen but subject to REACH restrictions as potential endocrine disruptor.

GHS Classification

H360 May damage fertility or the unborn child H315 Causes skin irritation

RIFM Assessment

RIFM assessment confirms sensitization potential at higher concentrations, supporting IFRA restrictions.

Sustainability

As a petrochemical derivative, dimethyl phthalate faces sustainability challenges. The industry is gradually replacing it with bio-based alternatives due to environmental persistence concerns and regulatory pressures. While effective, its use is declining in favor of more eco-friendly fixatives.

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References

  1. IFRA Standards Library. 49th Amendment. IFRA
  2. EU REACH Regulation (EC) No 1907/2006 ECHA
  3. Bickers et al. (2003). Safety assessment of dialkyl phthalates. Food Chem Toxicol. PMID 12804650

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 0131-11-3

Physical Properties

Molecular Weight194.18 g/mol🔬 PubChem
LogP (Octanol-Water)1.6🔬 PubChem
log Kp (skin permeability)-2.748💻 Calculated

Odor & Flavor

Primary Descriptorspear• leffingwell
“Very faint, ethereal odor. it hydrolyzes easily, producing a faint odor of Mipax.”📖 Arctander
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

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