Ethanone, 1-(1-cycloocten-1-yl)- (CAS 17339-74-1) — Woody Middle Note Fragrance Ingredient

Woody · Musky

Ethanone, 1-(1-cycloocten-1-yl)-

CAS 17339-74-1

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is Ethanone, 1-(1-cycloocten-1-yl)-?

Ethanone, 1-(1-cycloocten-1-yl)- is a synthetic fragrance ingredient primarily used in perfumery to add unique aromatic qualities. While not commonly encountered in everyday products, it may appear in niche or artisanal fragrances. This compound matters to perfumers for its ability to contribute complex, nuanced scents that are difficult to achieve with more common ingredients.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Safe when used in regulated concentrations
Limited safety data available
CAS
17339-74-1
Formula
Mixture
MW
Variable
Odor Family
Woody · Musky
Layer 1 · Enthusiast

What Does Ethanone, 1-(1-cycloocten-1-yl)- Smell Like?

Ethanone, 1-(1-cycloocten-1-yl)- offers a distinctive aroma characterized by its woody, slightly fruity, and musky notes. The scent evolves from a sharp, green top note to a heart of warm, resinous undertones, finishing with a dry, earthy base. Its complex profile makes it a versatile tool for perfumers seeking to create depth and intrigue in a fragrance.

Scent Profile
Layer 2

2D Molecular Structure

1-(1-Cycloocten-1-yl)ethanone

SMILES: CC(=O)C1=CCCCCCC1

Chemistry, Properties & Perfumer Guide

The Chemistry

Ethanone, 1-(1-cycloocten-1-yl)- is a synthetic ketone with a cyclooctene ring structure. It is typically synthesized through catalytic reactions involving cyclooctene and acetylating agents. The compound’s unique structure contributes to its complex olfactory profile, making it a valuable ingredient in niche perfumery.

Physical & Chemical Properties

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Used for complexity and depth

Classic Accords

Tip: Use sparingly to avoid overpowering other notes.

Alternatives & Comparisons

1
Cyclooctanone CAS 502-49-8

A simpler ketone with similar woody notes but less complexity.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions apply to this compound.

RIFM Assessment

Limited safety assessment data available from RIFM.

Sustainability

As a synthetic compound, Ethanone, 1-(1-cycloocten-1-yl)- is produced in controlled laboratory settings, minimizing environmental impact compared to some natural extracts. Its synthesis can be optimized for efficiency and reduced waste.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Physicochemical Properties

    DTXSID: DTXSID6075435

    Physical Properties

    Molecular Weight 152.237 g/mol🔬 EPA CompTox
    Density 0.935 g/cm^3📊 OPERA
    Boiling Point 230.88 °C📊 OPERA
    Melting Point 14.053 °C📊 OPERA
    Flash Point 91.726 °C📊 OPERA
    Refractive Index 1.468 Dimensionless📊 OPERA
    Molar Volume 164.467 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 2.886 Log10 unitless📊 OPERA
    LogD (pH 5.5) 2.886 Log10 unitless📊 OPERA
    LogD (pH 7.4) 2.886 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 5.69 Log10 unitless📊 OPERA
    Water Solubility 0.007 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0.104 mmHg📊 OPERA
    Surface Tension 33.116 dyn/cm📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 17.07 Ų💻 Computed
    H-Bond Donors 0 count💻 Computed
    H-Bond Acceptors 1 count💻 Computed
    Rotatable Bonds 1 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 45.699 cm^3/mol📊 OPERA
    Polarizability 18.116 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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