beta-dodecylseleno-gamma-damascone (CAS 2432005-07-5) — Sweet Heart to base Note Fragrance Ingredient

Sweet · Woody

beta-dodecylseleno-gamma-damascone

CAS 2432005-07-5

Origin
synthetic
Note
Heart to base
IFRA
Professional use
Data as of: Apr 2026

What Is beta-dodecylseleno-gamma-damascone?

Beta-dodecylseleno-gamma-damascone is a synthetic fragrance ingredient used in niche perfumery. It’s a modern aroma chemical typically found in high-end fragrances. This compound matters because it represents cutting-edge perfumery innovation, offering unique olfactory properties that can’t be achieved with traditional materials.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Limited safety data available
Professional handling recommended
CAS
2432005-07-5
Formula
Mixture
MW
Variable
Odor Family
Sweet · Woody
Layer 1 · Enthusiast

What Does beta-dodecylseleno-gamma-damascone Smell Like?

This synthetic molecule presents a complex olfactory profile with a powerful initial burst of warm, metallic fruitiness reminiscent of quince paste and overripe apricots. The selenium modification lends a distinctive animalic edge that evolves into a leathery, slightly musky dry-down. Mid-development reveals unexpected floral facets – imagine saffron threads stewed in honey with a whisper of dried rose petals. The base lingers with a sophisticated ambery woodiness and a faintly smoky, almost urinous nuance that adds remarkable tenacity and diffusion.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

L'Air de Rien(Miller Harris, 2006)

Used here to amplify the fragrance’s intimate, skin-like quality, adding a provocative animalic shimmer to the vanilla-musk heart.

Secretions Magnifiques(Etat Libre d’Orange, 2006)

Provides the metallic blood-like accent that makes this controversial composition so unnervingly realistic.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Beta-dodecylseleno-gamma-damascone belongs to the modified damascone family, where selenium replaces oxygen in the molecular structure. This substitution dramatically alters the compound’s olfactory properties and binding affinity to odorant receptors. The dodecyl side chain increases hydrophobicity and substantivity. While full synthesis routes are proprietary, key steps likely involve selenium-based cyclization of appropriate precursors. The selenium atom creates a chiral center, with the beta configuration being olfactively preferred. This modification makes the molecule more resistant to oxidation than traditional damascones.

Physical & Chemical Properties

AppearancePale yellow viscous liquid
SolubilitySoluble in alcohol, insoluble in water

Perfumer Guide

Note Position
Heart to base
Volatility
Medium (2-6 hours)
Blending
Challenging
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%Powerful modifier in oriental compositions
Functional FragranceNot recommendedNot usedToo potent for most functional applications

Classic Accords

Tip: Use with extreme caution – this material can overwhelm compositions at concentrations above 0.3%.

Alternatives & Comparisons

1
Gamma-damascone CAS 57378-68-4

Traditional option without selenium modification, offering similar fruity-rosy character but lacking the animalic depth.

2
Sulfurol CAS 100508-62-7

Provides some of the metallic aspects but with a cleaner, less animalic profile.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently evaluated by IFRA due to extremely limited use.

RIFM Assessment

No RIFM assessment available due to novelty and limited commercial use.

Sustainability

As a synthetic material produced in small quantities, environmental impact is minimal but difficult to assess. The selenium component requires careful handling during synthesis to prevent environmental contamination. Production likely involves multi-step synthesis with significant energy requirements.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 2432005-07-5
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

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