Ethyl 2,3,6,6-tetramethylcyclohex-2-ene-1-carboxylate (CAS 77851-07-01) — Woody Base Note Fragrance Ingredient

Woody · Balsamic

Ethyl 2,3,6,6-tetramethylcyclohex-2-ene-1-carboxylate

CAS 77851-07-01

Origin
synthetic
Note
Base
IFRA
Generally safe
Data as of: Apr 2026

What Is Ethyl 2,3,6,6-tetramethylcyclohex-2-ene-1-carboxylate?

Ethyl 2,3,6,6-tetramethylcyclohex-2-ene-1-carboxylate is a synthetic fragrance ingredient used to add woody, amber-like nuances to perfumes. It’s found in premium body care products and niche fragrances. This molecule matters because it creates sophisticated dry-down effects, enhancing longevity without overpowering other notes.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Check IFRA restrictions for specific applications
CAS
77851-07-01
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does Ethyl 2,3,6,6-tetramethylcyclohex-2-ene-1-carboxylate Smell Like?

This synthetic molecule opens with a crisp, woody-green character reminiscent of freshly split cedar planks. As it evolves, the scent reveals a warm, slightly sweet amber undertone, like sun-warmed tree resin. The dry-down is smooth and persistent, with a subtle musky nuance that blends seamlessly with other base notes.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Ethyl 2,3,6,6-tetramethylcyclohex-2-ene-1-carboxylate is a synthetic ester derived from modified cyclohexene structures. Its production typically involves Diels-Alder reactions followed by esterification. The tetramethyl substitution pattern creates steric hindrance that contributes to its unique odor profile and stability in formulations.

Physical & Chemical Properties

Perfumer Guide

Note Position
Base
Volatility
Low (hours-days)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 10%Adds woody-amber depth
Body Care0.5-2%Up to 3%Enhances longevity

Classic Accords

Tip: Use with citrus top notes to create contrast and complexity.

Alternatives & Comparisons

1
Iso E Super CAS 54464-57-2

When a more diffuse woody-amber effect is desired.

2
Ambroxan CAS 6790-58-5

For a cleaner, more transparent amber character.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No current IFRA restrictions.

RIFM Assessment

Not currently assessed by RIFM.

Sustainability

As a synthetic material, this ingredient avoids natural resource depletion. Production should follow green chemistry principles to minimize environmental impact.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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