Hexyl isobutyrate (CAS 2349-07-07) — Sweet Top Note Fragrance Ingredient
Hexyl isobutyrate
CAS 2349-07-07
What Is Hexyl isobutyrate?
Hexyl isobutyrate is a synthetic fragrance ingredient commonly used in fruity and floral perfumes, as well as in flavored foods and beverages. It imparts a sweet, fruity aroma reminiscent of ripe apples and pears. This ester is valued for its ability to add naturalistic fruit nuances to compositions without being overpowering, making it a versatile tool for perfumers and flavorists alike.
Safety Profile
GENERALLY SAFEWhat Does Hexyl isobutyrate Smell Like?
Hexyl isobutyrate bursts forth with an immediate, juicy fruitiness – think biting into a perfectly ripe Bartlett pear with hints of green apple skin. The top note has a sparkling quality that gradually softens into a more rounded, jammy fruit character. As it dries down, it reveals a subtle green freshness that prevents the sweetness from becoming cloying. The dry-down maintains a delicate fruity whisper that blends beautifully with floral and woody notes.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used to enhance the crisp apple top note, adding naturalistic fruitiness that complements the citrus opening and floral heart.
Provides subtle pear-like fruitiness that softens the floral bouquet and creates a more approachable, youthful character.
Chemistry, Properties & Perfumer Guide
The Chemistry
Hexyl isobutyrate is an ester formed from isobutyric acid and hexanol. As a synthetic material, it’s typically produced via acid-catalyzed esterification. The molecule lacks chiral centers, making stereochemistry irrelevant for this compound. Its relatively simple structure contributes to excellent stability in formulations while providing intense fruity odor characteristics at low concentrations.
Physical & Chemical Properties
| Appearance | Colorless liquid |
|---|---|
| Boiling Point | 198-200 °C |
| Density | 0.86 g/cm³ |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-2% | Up to 5% | Fruit note enhancer |
| Functional Fragrance | 0.1-0.5% | Up to 1% | Freshness booster |
Classic Accords
Tip: Use in trace amounts to brighten floral compositions without dominating the blend.
Alternatives & Comparisons
More banana-like fruit character with higher volatility, useful when a lighter, more fleeting fruit note is desired.
Stronger, more concentrated fruity effect with pineapple nuances, but requires more careful dosing due to potency.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No restrictions under current IFRA standards.
RIFM Assessment
Considered safe for current use levels based on RIFM assessment.
Sustainability
As a synthetic material, hexyl isobutyrate has consistent quality and doesn’t require agricultural land. Production typically uses petrochemical feedstocks, though bio-based routes from fermentation-derived alcohols are becoming available. Its efficiency at low concentrations makes it environmentally favorable compared to some natural extracts.
Explore Hexyl isobutyrate
Browse essential oils and aroma compounds.
Browse on iHerb →Affiliate disclosure: we may earn a small commission at no extra cost to you.
References
- Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data error
