Poly(oxy-1,2-ethanediyl), .alpha.-[3,5-dimethyl-1-(2-methylpropyl)hexyl]-.omega.-hydroxy- (CAS 60828-78-6) — Citrus Fixative Note Fragrance Ingredient

Citrus · Floral

Poly(oxy-1,2-ethanediyl), .alpha.-[3,5-dimethyl-1-(2-methylpropyl)hexyl]-.omega.-hydroxy-

CAS 60828-78-6

Origin
synthetic
Note
Fixative
IFRA
Generally safe
Data as of: Apr 2026

What Is Poly(oxy-1,2-ethanediyl), .alpha.-[3,5-dimethyl-1-(2-methylpropyl)hexyl]-.omega.-hydroxy-?

This synthetic polymer is used as a fixative in fragrances to prolong scent longevity. It is found in high-end perfumes and body sprays. The ingredient helps stabilize volatile fragrance components, ensuring the scent profile remains consistent throughout wear. Its ability to extend fragrance performance makes it valuable in modern perfumery.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Check for skin compatibility
CAS
60828-78-6
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does Poly(oxy-1,2-ethanediyl), .alpha.-[3,5-dimethyl-1-(2-methylpropyl)hexyl]-.omega.-hydroxy- Smell Like?

This ingredient is odorless but acts as a fixative, enhancing the longevity of other fragrance components. It works by slowing the evaporation of volatile top and heart notes, allowing the scent to unfold gradually. Its presence is felt through the extended duration of the fragrance rather than any distinct aroma.

Layer 2

2D Molecular Structure

Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether

SMILES: CC(C)CC(C)CC(CC(C)C)OCCO |lp:12:2,15:2,Sg:n:12,13,14::ht|

Chemistry, Properties & Perfumer Guide

The Chemistry

This synthetic polymer is derived from ethylene oxide and a branched alkyl group. It functions as a non-volatile fixative in perfumery, forming a film that traps fragrance molecules. The polymer’s structure allows it to interact with both polar and non-polar scent components, enhancing their persistence on the skin.

Physical & Chemical Properties

AppearanceColorless viscous liquid
SolubilitySoluble in alcohol and oils

Perfumer Guide

Note Position
Fixative
Volatility
Non-volatile
Blending
Excellent
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Extends longevity
Body Sprays0.5-2%Up to 3%Stabilizes scent

Classic Accords

Tip: Use as a fixative to enhance the longevity of volatile top notes.

Alternatives & Comparisons

1
Polyethylene Glycol CAS 25322-68-3

A more common fixative with similar properties but different molecular weight distribution.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions apply to this ingredient.

RIFM Assessment

No RIFM safety assessment available.

Sustainability

Synthesized from petrochemical sources, this ingredient is not biodegradable. Its environmental impact is mitigated by its low usage levels in formulations.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 60828-78-6

    Physical Properties

    Molecular Weight230.39 g/mol🔬 PubChem
    LogP (Octanol-Water)4.2🔬 PubChem
    log Kp (skin permeability)-1.123💻 Calculated
    SMILESCC(C)CC(C)CC(CC(C)C)OCCO🔬 PubChem

    Odor & Flavor

    Functional Groupsalcoholether💻 RDKit
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID9049829

    Physical Properties

    Molecular Weight 230.39 g/mol🔬 PubChem

    Partition & Solubility

    LogP (Octanol-Water) 3.482 dimensionless💻 Computed

    Molecular Descriptors

    Topological Polar Surface Area 29.46 Ų💻 Computed
    H-Bond Donors 1 count💻 Computed
    H-Bond Acceptors 2 count💻 Computed
    Rotatable Bonds 9 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 69.52 cm^3/mol💻 Computed

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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