Tetrahydrofurfuryl Butyrate (CAS 2217-33-6) — Mid Note Fragrance Ingredient



fruity

Tetrahydrofurfuryl Butyrate

CAS 2217-33-6

Note
mid
Volatility
medium
MW
172.2
Data as of: Jun 2026

What Is Tetrahydrofurfuryl Butyrate?

Tetrahydrofurfuryl Butyrate (CAS 2217-33-6) is an aroma chemical used as a fragrance and flavour ingredient. Its odour is described as bakery, sweet and garlic, placing it within the fruity family as a mid note with medium volatility. With a molecular weight of 172.2 (formula C9H16O3), it is handled by perfumers as a building block for compositions where a bakery character is desired. The data below is compiled from public chemical and regulatory sources.

Safety Profile

HANDLE WITH CARE

Generally safeUse with awarenessProfessional use
CAS
2217-33-6
Formula
C9H16O3
MW
172.2
InChIKey
DPZVDLFOAZNCBU-UHFFFAOYNA-N
Tetrahydrofurfuryl Butyrate 2D structure

Tetrahydrofurfuryl Butyrate
C9H16O3
Layer 1 · Enthusiast

What Does Tetrahydrofurfuryl Butyrate Smell Like?

The odour profile of Tetrahydrofurfuryl Butyrate is reported as bakery, sweet, garlic, spices, cold, sour, burnt, acid, warm, musky, sweaty, ammonia/urinous, decayed, wood, grass, flower, chemical, edible, fruity. The dominant facet is its bakery character, with the remaining notes adding nuance and complexity. As a mid note it contributes to the heart of a fragrance. Perceived intensity and exact character depend on concentration, the carrier and the surrounding accord.

Scent Profile

Profile derived from public odour-descriptor data; relative, not absolute.

Layer 2

Chemistry & Properties

The Chemistry

Tetrahydrofurfuryl Butyrate has the molecular formula C9H16O3 and a molecular weight of 172.2 g/mol. Its canonical SMILES representation is CCCC(=O)OCC1CCCO1. Its reported log P (XLogP) of 1.51 indicates a moderately polar molecule, which informs how it partitions in a formula. Physical constants below are drawn from PubChem and EPA CompTox public datasets.

Physical & Chemical Properties

Molecular Weight 172.2 g/mol
Boiling Point 215.4 °C
Melting Point -40.50 °C
Flash Point 92.56 °C
Density 1.20 g/cm³
Vapor Pressure 0.08057 mmHg
Water Solubility 0.035 g/L
XLogP 1.51

Perfumer Guide

Note Position
Mid
Volatility
Medium
Primary Odour
Bakery

Alternatives & Comparisons

Ingredients occupying a similar odour space — useful as substitutes or companions when Tetrahydrofurfuryl Butyrate is unavailable or restricted.

1
Potassium Sorbate CAS 24634-61-5

Shares acid, ammonia/urinous, bakery character — a candidate substitute or companion in the same odour space.

2
Isopentylamine CAS 107-85-7

Shares bakery, sweet, fish character — a candidate substitute or companion in the same odour space.

3
2-Acetyl-3-Ethylpyrazine CAS 32974-92-8

Shares bakery, sweet, fish character — a candidate substitute or companion in the same odour space.

Layer 3

Safety & Regulatory

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH and EU Cosmetics Regulation standards update periodically. Consult the current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

No IFRA restriction recorded in the data set. This is not a guarantee of unrestricted status — always confirm against the current IFRA Standards Library.

GHS Classification

Signal word: Warning

H302
Formulating with Tetrahydrofurfuryl Butyrate?

Open Tetrahydrofurfuryl Butyrate in Fragrance Studio (Pro) for the calibrated vapour-pressure curve, the modelled odour-threshold estimate, and the substitute-matching engine across 2,900+ aromachemicals.

Open in Fragrance Studio →

Free · Web-based · No install required

References & Sources

  1. PubChem Compound Summary (NIH) — search by InChIKey
  2. EPA CompTox Chemicals Dashboard — physicochemical & fate data
  3. IFRA Standards Library (49th / 51st Amendment)
Sources: PubChem (NIH) · EPA CompTox · IFRA Standards Library · public GHS classification. Odour descriptors are original editorial summaries of public profiles, not reproduced from any single proprietary source.

Data: PubChem (NIH), EPA CompTox, IFRA. Last reviewed: Jun 2026.

Report a data error

Similar Posts