Tetrahydrofurfuryl Acetate (CAS 637-64-9) — Mid Note Fragrance Ingredient
Tetrahydrofurfuryl Acetate
CAS 637-64-9
What Is Tetrahydrofurfuryl Acetate?
Tetrahydrofurfuryl Acetate (CAS 637-64-9) is an aroma chemical used as a fragrance and flavour ingredient. Its odour is described as bakery, sweet and fruit, placing it within the fruity family as a mid note with high volatility. With a molecular weight of 144.2 (formula C7H12O3), it is handled by perfumers as a building block for compositions where a bakery character is desired. The data below is compiled from public chemical and regulatory sources.
Safety Profile
HANDLE WITH CARE
What Does Tetrahydrofurfuryl Acetate Smell Like?
The odour profile of Tetrahydrofurfuryl Acetate is reported as bakery, sweet, fruit, fish, garlic, spices, cold, sour, burnt, acid, warm, musky, sweaty, ammonia/urinous, decayed, wood, grass, flower, chemical, edible. The dominant facet is its bakery character, with the remaining notes adding nuance and complexity. As a mid note it contributes to the heart of a fragrance. Perceived intensity and exact character depend on concentration, the carrier and the surrounding accord.
Scent Profile
Profile derived from public odour-descriptor data; relative, not absolute.
Chemistry & Properties
The Chemistry
Tetrahydrofurfuryl Acetate has the molecular formula C7H12O3 and a molecular weight of 144.2 g/mol. Its canonical SMILES representation is CC(=O)OCC1CCCO1. Its reported log P (XLogP) of 0.7285 indicates a moderately polar molecule, which informs how it partitions in a formula. Physical constants below are drawn from PubChem and EPA CompTox public datasets.
Physical & Chemical Properties
| Molecular Weight | 144.2 g/mol |
|---|---|
| Boiling Point | 193.0 °C |
| Melting Point | -40.25 °C |
| Flash Point | 74.01 °C |
| Density | 1.06 g/cm³ |
| Vapor Pressure | 0.257 mmHg |
| Water Solubility | 0.4786 g/L |
| XLogP | 0.7285 |
Perfumer Guide
Alternatives & Comparisons
Ingredients occupying a similar odour space — useful as substitutes or companions when Tetrahydrofurfuryl Acetate is unavailable or restricted.
Shares bakery, sweet, fruit character — a candidate substitute or companion in the same odour space.
Shares bakery, sweet, fruit character — a candidate substitute or companion in the same odour space.
Shares acid, ammonia/urinous, bakery character — a candidate substitute or companion in the same odour space.
Safety & Regulatory
⚠ Regulatory Disclaimer
General reference only. IFRA, REACH and EU Cosmetics Regulation standards update periodically. Consult the current IFRA Standards Library before formulating. Not legal or regulatory advice.
IFRA Status
No IFRA restriction recorded in the data set. This is not a guarantee of unrestricted status — always confirm against the current IFRA Standards Library.
GHS Classification
Signal word: Warning
Open Tetrahydrofurfuryl Acetate in Fragrance Studio (Pro) for the calibrated vapour-pressure curve, the modelled odour-threshold estimate, and the substitute-matching engine across 2,900+ aromachemicals.
References & Sources
- PubChem Compound Summary (NIH) — search by InChIKey
- EPA CompTox Chemicals Dashboard — physicochemical & fate data
- IFRA Standards Library (49th / 51st Amendment)
Data: PubChem (NIH), EPA CompTox, IFRA. Last reviewed: Jun 2026.
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