S-(1-Methylpropyl) 3-methylbut-2-enethioate (CAS 34322-09-03) — Sweet Top to middle Note Fragrance Ingredient

Sweet · Balsamic

S-(1-Methylpropyl) 3-methylbut-2-enethioate

CAS 34322-09-03

Origin
synthetic
Note
Top to middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is S-(1-Methylpropyl) 3-methylbut-2-enethioate?

S-(1-Methylpropyl) 3-methylbut-2-enethioate is a synthetic fragrance compound primarily used in perfumery. It’s encountered in niche fragrances and specialty formulations. This ingredient matters because it contributes unique sulfurous-fruity nuances that are difficult to achieve with more common materials, allowing perfumers to create distinctive accords.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
IFRA compliant at standard usage levels
Contains sulfur – may cause sensitivity
CAS
34322-09-03
Formula
Mixture
MW
Variable
Odor Family
Sweet · Balsamic
Layer 1 · Enthusiast

What Does S-(1-Methylpropyl) 3-methylbut-2-enethioate Smell Like?

A complex interplay of tropical fruit and sulfury depth, reminiscent of overripe passionfruit with a savory edge. Opens with a burst of juicy mango skin and catty intensity, settling into a warm, musky base with hints of blackcurrant bud. The sulfur character provides a lingering animalic trail that enhances longevity without overpowering.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

This thioester belongs to the class of sulfur-containing fragrance compounds, synthesized through esterification of 3-methyl-2-butenethiol with sec-butyl alcohol. The sulfur linkage provides enhanced volatility and impact compared to oxygen esters. The branched structure creates steric hindrance that influences both odor character and stability against hydrolysis.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
Boiling PointEstimated 180-200°C
DensityApprox. 0.92 g/cm³

Perfumer Guide

Note Position
Top to middle
Volatility
Moderate (2-4 hours)
Blending
Challenging
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%Powerful modifier
Functional Fragrance0.01-0.1%Up to 0.3%Trace amounts sufficient

Classic Accords

Tip: Use in micro-doses to avoid overwhelming compositions; excellent for adding tropical dimensionality to fruity florals.

Alternatives & Comparisons

1
Methyl 3-methylbut-2-enethioate CAS 42075-45-6

Similar sulfur-fruit character but more diffusive and less tenacious.

2
Ethyl 3-methylbut-2-enethioate CAS 42075-44-5

Softer, rounder version with less animalic impact.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards.

RIFM Assessment

No specific RIFM assessment found; general thioester safety guidelines apply.

Sustainability

As a synthetic material, production avoids agricultural land use. However, sulfur chemistry requires careful waste management. The compound’s potency means small quantities suffice, reducing overall environmental load compared to less powerful ingredients.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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