2,5-Diethyl-3-Methylpyrazine (CAS 32736-91-7) — Mid Note Fragrance Ingredient
2,5-Diethyl-3-Methylpyrazine
CAS 32736-91-7
What Is 2,5-Diethyl-3-Methylpyrazine?
2,5-Diethyl-3-Methylpyrazine (CAS 32736-91-7) is an aroma chemical used as a fragrance and flavour ingredient. Its odour is described as burnt, hazelnut and nutty, placing it within the gourmand family as a mid note with medium volatility. With a molecular weight of 150.2 (formula C9H14N2), it is handled by perfumers as a building block for compositions where a burnt character is desired. The data below is compiled from public chemical and regulatory sources.
Safety Profile
HANDLE WITH CARE
What Does 2,5-Diethyl-3-Methylpyrazine Smell Like?
The odour profile of 2,5-Diethyl-3-Methylpyrazine is reported as burnt, hazelnut, nutty, potato, roasted, earthy, green. The dominant facet is its burnt character, with the remaining notes adding nuance and complexity. As a mid note it contributes to the heart of a fragrance. Perceived intensity and exact character depend on concentration, the carrier and the surrounding accord.
Scent Profile
Profile derived from public odour-descriptor data; relative, not absolute.
Chemistry & Properties
The Chemistry
2,5-Diethyl-3-Methylpyrazine has the molecular formula C9H14N2 and a molecular weight of 150.2 g/mol. Its canonical SMILES representation is CCC1=CN=C(CC)C(C)=N1. Its reported log P (XLogP) of 1.91 indicates a moderately polar molecule, which informs how it partitions in a formula. Physical constants below are drawn from PubChem and EPA CompTox public datasets.
Physical & Chemical Properties
| Molecular Weight | 150.2 g/mol |
|---|---|
| Boiling Point | 206.6 °C |
| Melting Point | 35.51 °C |
| Flash Point | 80.20 °C |
| Density | 0.949 g/cm³ |
| Vapor Pressure | 0.1464 mmHg |
| Water Solubility | 0.1514 g/L |
| XLogP | 1.91 |
Perfumer Guide
Alternatives & Comparisons
Ingredients occupying a similar odour space — useful as substitutes or companions when 2,5-Diethyl-3-Methylpyrazine is unavailable or restricted.
Shares potato, roasted, nutty character — a candidate substitute or companion in the same odour space.
Shares earthy, green, nutty character — a candidate substitute or companion in the same odour space.
Shares earthy, green, nutty character — a candidate substitute or companion in the same odour space.
Safety & Regulatory
⚠ Regulatory Disclaimer
General reference only. IFRA, REACH and EU Cosmetics Regulation standards update periodically. Consult the current IFRA Standards Library before formulating. Not legal or regulatory advice.
IFRA Status
No IFRA restriction recorded in the data set. This is not a guarantee of unrestricted status — always confirm against the current IFRA Standards Library.
GHS Classification
Signal word: Warning
Open 2,5-Diethyl-3-Methylpyrazine in Fragrance Studio (Pro) for the calibrated vapour-pressure curve, the modelled odour-threshold estimate, and the substitute-matching engine across 2,900+ aromachemicals.
References & Sources
- PubChem Compound Summary (NIH) — search by InChIKey
- EPA CompTox Chemicals Dashboard — physicochemical & fate data
- IFRA Standards Library (49th / 51st Amendment)
Data: PubChem (NIH), EPA CompTox, IFRA. Last reviewed: Jun 2026.
Related Research
- Mandarin oil terpenes (CAS 68953-04-08) — Citrus Top Note Fragrance Ingredient
- 2,3-Dimethylphenol (CAS 526-75-0) — Woody Middle to base Note Fragrance Ingredient
- (4-tert-Butylphenyl)acetonitrile (CAS 3288-99-1) — Green Middle Note Fragrance Ingredient
- 9-Decen-2-one (CAS 35194-30-0) — Citrus Top Note Fragrance Ingredient
