2,5-Dimethyl-3-Furanthiol (CAS 55764-23-3) — Top Note Fragrance Ingredient

ByThe Good Scents



gourmand

2,5-Dimethyl-3-Furanthiol

CAS 55764-23-3

Note
top
Volatility
high
MW
128.2
Data as of: Jun 2026

What Is 2,5-Dimethyl-3-Furanthiol?

2,5-Dimethyl-3-Furanthiol (CAS 55764-23-3) is an aroma chemical used as a fragrance and flavour ingredient. Its odour is described as sweet, fish and garlic, placing it within the gourmand family as a top note with high volatility. With a molecular weight of 128.2 (formula C6H8OS), it is handled by perfumers as a building block for compositions where a sweet character is desired. The data below is compiled from public chemical and regulatory sources.

Safety Profile

HANDLE WITH CARE

Generally safeUse with awarenessProfessional use
CAS
55764-23-3
Formula
C6H8OS
MW
128.2
InChIKey
DBBHCZMXKBCICL-UHFFFAOYSA-N
2,5-Dimethyl-3-Furanthiol 2D structure

2,5-Dimethyl-3-Furanthiol
C6H8OS
Layer 1 · Enthusiast

What Does 2,5-Dimethyl-3-Furanthiol Smell Like?

The odour profile of 2,5-Dimethyl-3-Furanthiol is reported as sweet, fish, garlic, burnt, meaty, sulfurous. The dominant facet is its sweet character, with the remaining notes adding nuance and complexity. As a top note it contributes to the opening of a fragrance. Perceived intensity and exact character depend on concentration, the carrier and the surrounding accord.

Scent Profile

Profile derived from public odour-descriptor data; relative, not absolute.

Layer 2

Chemistry & Properties

The Chemistry

2,5-Dimethyl-3-Furanthiol has the molecular formula C6H8OS and a molecular weight of 128.2 g/mol. Its canonical SMILES representation is CC1=CC(S)=C(C)O1. Its reported log P (XLogP) of 2.19 indicates a lipophilic, oil-soluble molecule, which informs how it partitions in a formula. Physical constants below are drawn from PubChem and EPA CompTox public datasets.

Physical & Chemical Properties

Molecular Weight 128.2 g/mol
Boiling Point 187.0 °C
Melting Point 21.20 °C
Flash Point 63.74 °C
Density 1.14 g/cm³
Vapor Pressure 1.91 mmHg
Water Solubility 0.008945 g/L
XLogP 2.19

Perfumer Guide

Note Position
Top
Volatility
High
Primary Odour
Sweet

Alternatives & Comparisons

Ingredients occupying a similar odour space — useful as substitutes or companions when 2,5-Dimethyl-3-Furanthiol is unavailable or restricted.

1
Methyl Propyl Disulfide CAS 2179-60-4

Shares sulfurous, onion, garlic character — a candidate substitute or companion in the same odour space.

2
2-Ethylfuran CAS 3208-16-0

Shares burnt, ethereal, sweet character — a candidate substitute or companion in the same odour space.

3
Furfuryl Thioacetate CAS 13678-68-7

Shares burnt, garlic, roasted character — a candidate substitute or companion in the same odour space.

Layer 3

Safety & Regulatory

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH and EU Cosmetics Regulation standards update periodically. Consult the current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

No IFRA restriction recorded in the data set. This is not a guarantee of unrestricted status — always confirm against the current IFRA Standards Library.

GHS Classification

Signal word: Warning

H226H302
Formulating with 2,5-Dimethyl-3-Furanthiol?

Open 2,5-Dimethyl-3-Furanthiol in Fragrance Studio (Pro) for the calibrated vapour-pressure curve, the modelled odour-threshold estimate, and the substitute-matching engine across 2,900+ aromachemicals.

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References & Sources

  1. PubChem Compound Summary (NIH) — search by InChIKey
  2. EPA CompTox Chemicals Dashboard — physicochemical & fate data
  3. IFRA Standards Library (49th / 51st Amendment)
Sources: PubChem (NIH) · EPA CompTox · IFRA Standards Library · public GHS classification. Odour descriptors are original editorial summaries of public profiles, not reproduced from any single proprietary source.

Data: PubChem (NIH), EPA CompTox, IFRA. Last reviewed: Jun 2026.

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