2-Methyl-4-phenyl-1,3-dioxolane (CAS 33941-99-0) — Green Top to middle Note Fragrance Ingredient
2-Methyl-4-phenyl-1,3-dioxolane
CAS 33941-99-0
What Is 2-Methyl-4-phenyl-1,3-dioxolane?
2-Methyl-4-phenyl-1,3-dioxolane is a synthetic fragrance ingredient used to add fresh, green, and slightly floral nuances to perfumes. It’s found in various personal care products like body sprays and fabric softeners. This molecule helps create crisp, clean scent profiles that mimic natural aromas without relying on plant extracts.
Safety Profile
GENERALLY SAFEWhat Does 2-Methyl-4-phenyl-1,3-dioxolane Smell Like?
2-Methyl-4-phenyl-1,3-dioxolane opens with a crisp, dewy freshness reminiscent of crushed green stems and morning fog. The heart reveals a delicate floralcy akin to lily-of-the-valley petals floating in rainwater, supported by a subtle woody-herbal undertone. As it dries, the fragrance settles into a clean, slightly sweet muskiness with the faintest hint of rosewater. The overall effect is transparent and diffusive, like sunlight filtering through spring foliage.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used here to enhance the crisp green tea accord with its dewy freshness, complementing citrus top notes while adding dimensionality to the floral heart.
Contributes to the watery floralcy of this iconic aquatic fragrance, helping bridge the citrus top to lotus flower heart notes.
2D Molecular Structure
SMILES: CC1OCC(O1)C1=CC=CC=C1
Chemistry, Properties & Perfumer Guide
The Chemistry
2-Methyl-4-phenyl-1,3-dioxolane belongs to the dioxolane class of cyclic acetals, formed through acid-catalyzed reactions between glycols and carbonyl compounds. Its structure features a phenyl group at the 4-position and methyl substitution at the 2-position, creating a chiral center that influences odor characteristics. Industrial synthesis typically involves condensation of benzaldehyde with propylene glycol under acidic conditions.
Physical & Chemical Properties
| Boiling Point | Not available |
|---|---|
| Density | Not available |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 1-3% | Up to 5% | Fresh floral modifier |
| Functional Products | 0.1-0.5% | Up to 1% | Clean scent booster |
Classic Accords
Tip: Use to lift and brighten white floral compositions without adding heaviness.
Alternatives & Comparisons
Provides comparable floral green notes with stronger hyacinth character.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not currently restricted by IFRA standards.
RIFM Assessment
Currently under review by RIFM with preliminary data suggesting low sensitization potential.
Sustainability
As a synthetic material, 2-methyl-4-phenyl-1,3-dioxolane reduces pressure on natural resources. Production typically uses petrochemical feedstocks, though some manufacturers are exploring bio-based routes. The material’s efficiency at low concentrations makes it environmentally favorable compared to some natural alternatives.
Explore 2-Methyl-4-phenyl-1,3-dioxolane
Browse essential oils and aroma compounds.
Browse on iHerb →Affiliate disclosure: we may earn a small commission at no extra cost to you.
References
- Bauer et al. (2001). Modern Synthetic Methods in Fragrance Chemistry. Chemistry & Biodiversity.
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data errorPhysicochemical Properties
DTXSID: DTXSID00865696
Physical Properties
| Molecular Weight | 164.204 g/mol🔬 EPA CompTox |
| Density | 1.07 g/cm^3🔬 EPA CTX |
| Boiling Point | 242.093 °C📊 OPERA |
| Melting Point | 19.182 °C📊 OPERA |
| Flash Point | 97.5 °C🔬 EPA CTX |
| Refractive Index | 1.508 Dimensionless📊 OPERA |
| Molar Volume | 154.978 cm^3/mol📊 OPERA |
Partition & Solubility
| LogP (Octanol-Water) | 2.19 Log10 unitless🔬 EPA CTX |
| LogD (pH 5.5) | 2.303 Log10 unitless📊 OPERA |
| LogD (pH 7.4) | 2.303 Log10 unitless📊 OPERA |
| LogKoa (Octanol-Air) | 5.26 Log10 unitless📊 OPERA |
| Water Solubility | 0.016 mol/L🔬 EPA CTX |
| Henry's Law Constant | 0 atm-m3/mole📊 OPERA |
Transport Properties
| Vapor Pressure | 0.724 mmHg🔬 EPA CTX |
| Viscosity | 4.822 cP📊 OPERA |
| Surface Tension | 36.44 dyn/cm📊 OPERA |
| Thermal Conductivity | 129.564 mW/(m*K)📊 OPERA |
Molecular Descriptors
| Topological Polar Surface Area | 18.46 Ų💻 Computed |
| H-Bond Donors | 0 count💻 Computed |
| H-Bond Acceptors | 2 count💻 Computed |
| Rotatable Bonds | 1 count💻 Computed |
| Aromatic Rings | 1 count💻 Computed |
| Molar Refractivity | 46.198 cm^3/mol📊 OPERA |
| Polarizability | 18.314 Å^3📊 OPERA |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
