2-Propanol, 1,1′,1′,1′-(1,2-ethanediyldinitrilo)tetrakis- (CAS 102-60-3) — Citrus Non-aromatic Note Fragrance Ingredient

Citrus · Floral

2-Propanol, 1,1',1',1'-(1,2-ethanediyldinitrilo)tetrakis-

CAS 102-60-3

Origin
synthetic
Note
Non-aromatic
IFRA
Professional use
Data as of: Apr 2026

What Is 2-Propanol, 1,1',1',1'-(1,2-ethanediyldinitrilo)tetrakis-?

This synthetic compound is a specialized ingredient used primarily in industrial fragrance applications and chemical synthesis. Consumers rarely encounter it directly. As a chelating agent, it plays a behind-the-scenes role in stabilizing certain fragrance formulations rather than contributing directly to scent profiles.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Industrial handling precautions required
Not for consumer direct use
CAS
102-60-3
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does 2-Propanol, 1,1',1',1'-(1,2-ethanediyldinitrilo)tetrakis- Smell Like?

This compound is odorless in pure form, functioning as a chemical stabilizer rather than an aromatic material. Its primary role in fragrance applications is to chelate metal ions that might otherwise catalyze oxidation reactions in fragrance oils. The molecule exhibits no discernible top, middle, or base notes, nor does it contribute to dry-down characteristics in finished perfumes.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

This tetrapropanolamine derivative belongs to the polyol amine class, featuring four isopropanol groups attached to an ethylenediamine core. The molecule acts as a tetradentate ligand, forming stable complexes with transition metals. Industrial synthesis typically involves the reaction of ethylenediamine with excess propylene oxide under controlled conditions. The compound’s chelating properties make it valuable for stabilizing oxidation-prone fragrance components.

Physical & Chemical Properties

AppearanceColorless viscous liquid
FunctionChelating agent

Perfumer Guide

Note Position
Non-aromatic
Volatility
N/A
Blending
Stabilizing agent
ApplicationTypical %RangeNotes
Industrial Stabilizer0.1-0.5%Up to 1%Metal ion sequestration

Classic Accords

Tip: Use as a stabilizer in metal-sensitive formulations at minimal effective concentrations.

Alternatives & Comparisons

1
EDTA CAS 60-00-4

Ethylenediaminetetraacetic acid offers stronger chelation for more demanding stabilization requirements.

2
Citric acid CAS 77-92-9

Natural chelator suitable for cleaner-label formulations where mild stabilization suffices.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not regulated by IFRA as it is not an aromatic material.

GHS Classification

H315 Skin irritation H319 Eye irritation H335 Respiratory irritation

RIFM Assessment

Not evaluated by RIFM as it is not a fragrance material.

Sustainability

As a synthetic compound, this material is produced through petrochemical processes. While effective at low concentrations, its environmental impact is mitigated through controlled industrial handling. Green chemistry alternatives are being developed for similar chelating functions.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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