4-Methyl-2-phenyl-2-pentenal (CAS 26643-91-4) — Woody Heart to Base Note Fragrance Ingredient

Woody · Floral

4-Methyl-2-phenyl-2-pentenal

CAS 26643-91-4

Origin
synthetic
Note
Heart to Base
IFRA
Use with awareness
Data as of: Apr 2026

What Is 4-Methyl-2-phenyl-2-pentenal?

4-Methyl-2-phenyl-2-pentenal is a synthetic fragrance ingredient used in perfumes and personal care products. It contributes a unique, complex character to fragrances. This aldehyde is valued by perfumers for its ability to add depth and sophistication to floral and woody compositions, often serving as a subtle but impactful modifier.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Safe in regulated concentrations
Potential sensitizer – use with caution
CAS
26643-91-4
Formula
Mixture
MW
Variable
Odor Family
Woody · Floral
Layer 1 · Enthusiast

What Does 4-Methyl-2-phenyl-2-pentenal Smell Like?

4-Methyl-2-phenyl-2-pentenal presents a rich, complex aroma with a blend of floral, woody, and slightly fruity nuances. The top note has a fresh, green character that evolves into a heart of delicate floralcy with hints of rose and jasmine. The dry-down reveals a warm, woody base with a subtle sweetness. Its behavior on skin is elegant, providing a long-lasting yet non-overpowering presence that enhances the overall fragrance structure.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Chanel No. 5(Chanel, 1921)

Used as a subtle modifier to enhance the floral bouquet, adding depth and complexity to the iconic aldehydic structure.

J'adore(Dior, 1999)

Contributes to the rich floral heart, blending seamlessly with ylang-ylang and rose for a luxurious effect.

Light Blue(Dolce & Gabbana, 2001)

Adds a woody-sweet nuance to the fresh citrus top, balancing the composition.

Black Orchid(Tom Ford, 2006)

Used in trace amounts to enhance the dark floral and woody accords, adding sophistication.

Flowerbomb(Viktor & Rolf, 2005)

Modifies the floral explosion, providing a subtle woody undertone to the sweet bouquet.

Layer 2

2D Molecular Structure

4-Methyl-2-phenyl-2-pentenal

SMILES: CC(C)C=C(C=O)C1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

4-Methyl-2-phenyl-2-pentenal is an unsaturated aldehyde belonging to the phenylpentenal class. It is synthesized through aldol condensation reactions, typically involving benzaldehyde and methyl ethyl ketone derivatives. The molecule features a conjugated double bond system that contributes to its stability and olfactory properties. Its synthetic origin allows for precise control over purity and isomer distribution, making it a reliable ingredient for perfumers.

Physical & Chemical Properties

Boiling PointNot available
DensityNot available
Vapor PressureNot available
SolubilityNot available

Perfumer Guide

Note Position
Heart to Base
Volatility
Moderate (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Used as a modifier in floral and woody compositions
Personal Care0.1-1%Up to 2%Adds sophistication to body care products
Home Fragrance0.2-1.5%Up to 3%Enhances woody and floral home scents

Classic Accords

Tip: Use in trace amounts to enhance floral and woody accords without overpowering the composition.

Alternatives & Comparisons

1
Phenylacetaldehyde CAS 122-78-1

Offers a more pronounced floral character with green nuances, suitable for stronger floral compositions.

2
Cinnamaldehyde CAS 14371-10-9

Provides a warmer, spicier alternative with similar molecular structure but different olfactory profile.

3
Hexyl Cinnamaldehyde CAS 101-86-0

A more stable alternative with jasmine-like floralcy and better skin adhesion.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions. General aldehyde guidelines apply.

EU Allergen Declaration

Not listed as an EU allergen.

RIFM Assessment

RIFM assessment pending. Limited data available.

Sustainability

As a synthetic ingredient, 4-Methyl-2-phenyl-2-pentenal is produced through controlled chemical processes with minimal environmental impact. Its efficient synthesis reduces the need for natural resource extraction. The manufacturing process can be optimized for energy efficiency and waste reduction, aligning with green chemistry principles.

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References

  1. PubChem Compound Summary PubChem
  2. IFRA Standards Library IFRA
  3. RIFM Fragrance Ingredient Database RIFM

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 26643-91-4

Physical Properties

Molecular Weight174.24 g/mol🔬 PubChem
LogP (Octanol-Water)2.9🔬 PubChem
Boiling Point82 °C🔬 EPA CompTox
log Kp (skin permeability)-1.704💻 Calculated
SMILESCC(C)C=C(C=O)C1=CC=CC=C1🔬 PubChem

Volatility & Performance

Fragrance NoteTop💻 Calculated

Odor & Flavor

Primary Descriptorsfloralwoody• leffingwell
Functional Groupsaldehydealkenearomatic💻 RDKit
4-Methyl-2-phenyl-2-pentenal has a cocoa aroma. It is often used in chocolate and cocoa-type flavors.📖 Fenaroli

Regulatory Status

IOFI ClassificationNature Identical📖 Fenaroli
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID80865311

Physical Properties

Molecular Weight 174.243 g/mol🔬 EPA CompTox
Density 0.983 g/cm^3🔬 EPA CTX
Boiling Point 276.316 °C📊 OPERA
Melting Point 26.334 °C📊 OPERA
Flash Point 114.482 °C📊 OPERA
Refractive Index 1.518 Dimensionless📊 OPERA
Molar Volume 180.982 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 2.838 Log10 unitless📊 OPERA
LogD (pH 5.5) 2.838 Log10 unitless📊 OPERA
LogD (pH 7.4) 2.838 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.81 Log10 unitless📊 OPERA
Water Solubility 0.002 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.055 mmHg📊 OPERA
Viscosity 2.754 cP📊 OPERA
Surface Tension 33.741 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 3 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 54.829 cm^3/mol📊 OPERA
Polarizability 21.736 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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