Cinnamyl butyrate (CAS 103-61-7) — Sweet Middle Note Fragrance Ingredient

Sweet · Spicy

Cinnamyl butyrate

CAS 103-61-7

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is Cinnamyl butyrate?

Cinnamyl butyrate is a synthetic fragrance compound that mimics the warm, spicy-sweet aroma of cinnamon with a fruity twist. You’ll encounter it in gourmand perfumes, candle scents, and flavored products. This ingredient matters because it bridges the gap between food-inspired scents and traditional perfumery, creating inviting, comforting fragrances with excellent staying power.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
IFRA-approved for fragrance use
Potential skin sensitizer at high concentrations
CAS
103-61-7
Formula
Mixture
MW
Variable
Odor Family
Sweet · Spicy
Layer 1 · Enthusiast

What Does Cinnamyl butyrate Smell Like?

Cinnamyl butyrate bursts with a jammy cinnamon roll warmth – think melted butter on cinnamon toast with a drizzle of plum compote. The opening has a boozy, almost rum-like fruity intensity that mellows into a smooth balsamic heart. As it dries down, it reveals a creamy vanilla-amber base note that lingers like the memory of a spice market at dusk. Unlike raw cinnamon, it lacks harsh phenolic edges, instead offering a rounded sweetness that blends seamlessly with florals and woods.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Spicebomb(Viktor & Rolf, 2012)

Provides the addictive gourmand cinnamon core that makes this fragrance so craveable, blending with saffron and tobacco to create explosive warmth.

Angel Muse(Mugler, 2016)

Used as a bridge between the patchouli base and citrus top, adding a plush cinnamon-hazelnut dimension to the chocolate accord.

Layer 2

2D Molecular Structure

Cinnamyl butyrate

SMILES: CCCC(=O)OCC=CC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

Cinnamyl butyrate is an ester formed by the condensation of cinnamyl alcohol and butyric acid. As a synthetic molecule, it’s typically produced via Fischer esterification under acidic conditions. The ester linkage gives it greater stability than raw cinnamic aldehyde, while the butyrate side chain contributes to its creamy diffusion. Though not found in nature, its structural relatives occur in cinnamon bark and tropical fruits.

Physical & Chemical Properties

Boiling Point~300 °C (estimated)
Density~1.01 g/cm³ (estimated)

Perfumer Guide

Note Position
Middle
Volatility
Moderate (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Adds warmth to oriental bases
Candles1-3%Up to 8%Creates baked goods realism

Classic Accords

+ Vanilla + Tonka = Gourmand + Patchouli + Amber = Oriental + Citrus + Musk = Spiced Cologne

Tip: Use with white musks to prevent the spice from dominating the drydown.

Alternatives & Comparisons

1
Cinnamyl acetate CAS 103-54-8

For a brighter, less gourmand cinnamon effect with apple-like freshness.

2
Ethyl cinnamate CAS 103-36-6

When a softer, strawberry-like cinnamon is needed with better floral compatibility.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No restrictions under IFRA 51st Amendment. Typical use levels well below sensitization thresholds.

EU Allergen Declaration

Not classified as an EU allergen under Regulation (EC) No 1223/2009.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

RIFM evaluation confirms safe use at current industry levels with proper precautions.

Sustainability

As a fully synthetic material, cinnamyl butyrate avoids agricultural impacts of cinnamon cultivation. Production typically uses green chemistry principles with >90% atom economy. Being petroleum-derived, its carbon footprint depends on renewable energy use in manufacturing.

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References

  1. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 103-61-7

Physical Properties

Molecular Weight204.26 g/mol🔬 PubChem
LogP (Octanol-Water)3.1🔬 PubChem
Boiling Point300 °C🔬 EPA CompTox
Vapor Pressure0.0263 mmHg @ 25°C📊 OPERA
Flash Point131.9 °C🔬 EPA CompTox
Involatility Index0.002💻 Calculated
log Kp (skin permeability)-1.745💻 Calculated
SMILESCCCC(=O)OCC=CC1=CC=CC=C1🔬 PubChem

Volatility & Performance

Fragrance NoteBase💻 Calculated
Volatility ClassVery slow💻 Calculated
Persistence Score3 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsbalsamicfloralfruity• leffingwell
Functional Groupsesteretheralkenearomatic💻 RDKit
“Fruity-balsamic, rather faint, but actually heavy odor, resembling Phenylethyl butyrate, but less floral. The undertone is floral and rich, but the overall impression is fruity-balsamic.”📖 Arctander
Cinnamyl butyrate has a fruity, slightly floral odor and sweet taste reminiscent of honey. It is used in orange and citrus flavors.📖 Fenaroli

Flavor Notes (Arctander)

“Occasionally used in flavor compositions for imitation Orange, Citrus and Fruit (Tutti-frutti) flavors.”📖 Arctander

Sensory Thresholds

Odor Detection Threshold159 ppm📖 van Gemert

Regulatory Status

FEMA NumberFEMA 2296⚖️ FEMA GRAS
GRAS StatusGenerally Recognized as Safe⚖️ FEMA GRAS
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID2059277

Physical Properties

Molecular Weight 204.269 g/mol🔬 EPA CompTox
Density 1.02 g/cm^3🔬 EPA CTX
Boiling Point 300 °C🔬 EPA CTX
Melting Point 26.276 °C📊 OPERA
Flash Point 128.532 °C📊 OPERA
Refractive Index 1.537 Dimensionless📊 OPERA
Molar Volume 199.918 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 3.458 Log10 unitless📊 OPERA
LogD (pH 5.5) 3.458 Log10 unitless📊 OPERA
LogD (pH 7.4) 3.458 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 6.9 Log10 unitless📊 OPERA
Water Solubility 0.002 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.009 mmHg📊 OPERA
Viscosity 4.867 cP📊 OPERA
Surface Tension 36.375 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 26.3 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 2 count💻 Computed
Rotatable Bonds 5 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 62.449 cm^3/mol📊 OPERA
Polarizability 24.757 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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