cis-5-Octen-1-Ol (CAS 64275-73-6) — Mid Note Fragrance Ingredient
cis-5-Octen-1-Ol
CAS 64275-73-6
What Is cis-5-Octen-1-Ol?
cis-5-Octen-1-Ol (CAS 64275-73-6) is an aroma chemical used as a fragrance and flavour ingredient. Its odour is described as fruity, green and melon, placing it within the green family as a mid note with very high volatility. With a molecular weight of 128.2 (formula C8H16O), it is handled by perfumers as a building block for compositions where a fruity character is desired. The data below is compiled from public chemical and regulatory sources.
Safety Profile
USE WITH AWARENESS
What Does cis-5-Octen-1-Ol Smell Like?
The odour profile of cis-5-Octen-1-Ol is reported as fruity, green, melon, mushroom. The dominant facet is its fruity character, with the remaining notes adding nuance and complexity. As a mid note it contributes to the heart of a fragrance. Perceived intensity and exact character depend on concentration, the carrier and the surrounding accord.
Scent Profile
Profile derived from public odour-descriptor data; relative, not absolute.
2D Molecular Structure
SMILES: CC\C=C/CCCCO
Chemistry & Properties
The Chemistry
cis-5-Octen-1-Ol has the molecular formula C8H16O and a molecular weight of 128.2 g/mol. Its canonical SMILES representation is CC/C=C\CCCCO. Its reported log P (XLogP) of 2.00 indicates a moderately polar molecule, which informs how it partitions in a formula. Physical constants below are drawn from PubChem and EPA CompTox public datasets.
Physical & Chemical Properties
| Molecular Weight | 128.2 g/mol |
|---|---|
| Boiling Point | 191.5 °C |
| Melting Point | -7.50 °C |
| Flash Point | 76.05 °C |
| Density | 0.84 g/cm³ |
| Vapor Pressure | 0.0761 mmHg |
| Water Solubility | 0.01202 g/L |
| XLogP | 2.00 |
Perfumer Guide
Alternatives & Comparisons
Ingredients occupying a similar odour space — useful as substitutes or companions when cis-5-Octen-1-Ol is unavailable or restricted.
Shares fresh, fruity, green character — a candidate substitute or companion in the same odour space.
Shares fruity, green, melon character — a candidate substitute or companion in the same odour space.
Shares fruity, grassy, green character — a candidate substitute or companion in the same odour space.
Safety & Regulatory
⚠ Regulatory Disclaimer
General reference only. IFRA, REACH and EU Cosmetics Regulation standards update periodically. Consult the current IFRA Standards Library before formulating. Not legal or regulatory advice.
IFRA Status
No IFRA restriction recorded in the data set. This is not a guarantee of unrestricted status — always confirm against the current IFRA Standards Library.
GHS Classification
Signal word: Danger
Odour detection threshold (air): 0.006 ppb — a literature-curated value indicating its potency in the vapour phase.
Open cis-5-Octen-1-Ol in Fragrance Studio (Pro) for the calibrated vapour-pressure curve, the modelled odour-threshold estimate, and the substitute-matching engine across 2,900+ aromachemicals.
References & Sources
- PubChem Compound Summary (NIH) — search by InChIKey
- EPA CompTox Chemicals Dashboard — physicochemical & fate data
- IFRA Standards Library (49th / 51st Amendment)
Data: PubChem (NIH), EPA CompTox, IFRA. Last reviewed: Jun 2026.
Ingredient Data Sheet
CAS 64275-73-6Physical Properties
| Molecular Weight | 128.21 g/mol🔬 PubChem |
| LogP (Octanol-Water) | 2🔬 PubChem |
| Boiling Point | 95 °C🔬 EPA CompTox |
| log Kp (skin permeability) | -2.062💻 Calculated |
| SMILES | CCC=CCCCCO🔬 PubChem |
Volatility & Performance
| Fragrance Note | Top💻 Calculated |
Odor & Flavor
| Primary Descriptors | fruitygreenmelonmushroom• leffingwell |
| Functional Groups | alcoholalkene💻 RDKit |
| cis-5-Octen-1-ol has a green, fatty odor.📖 Fenaroli | |
Sensory Thresholds
| Odor Detection Threshold | 0.006 ppm📖 van Gemert |
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.
Physicochemical Properties
DTXSID: DTXSID9047700
Physical Properties
| Molecular Weight | 128.215 g/mol🔬 EPA CompTox |
| Density | 0.85 g/cm^3🔬 EPA CTX |
| Boiling Point | 192.862 °C📊 OPERA |
| Melting Point | -7.504 °C📊 OPERA |
| Flash Point | 76.052 °C📊 OPERA |
| Refractive Index | 1.449 Dimensionless📊 OPERA |
| Molar Volume | 151.71 cm^3/mol📊 OPERA |
Partition & Solubility
| LogP (Octanol-Water) | 2.198 Log10 unitless📊 OPERA |
| LogD (pH 5.5) | 2.198 Log10 unitless📊 OPERA |
| LogD (pH 7.4) | 2.198 Log10 unitless📊 OPERA |
| LogKoa (Octanol-Air) | 5.94 Log10 unitless📊 OPERA |
| Water Solubility | 0.013 mol/L📊 OPERA |
| Henry's Law Constant | 0 atm-m3/mole📊 OPERA |
Transport Properties
| Vapor Pressure | 0.086 mmHg📊 OPERA |
| Viscosity | 3.349 cP📊 OPERA |
| Surface Tension | 27.971 dyn/cm📊 OPERA |
| Thermal Conductivity | 148.851 mW/(m*K)📊 OPERA |
Molecular Descriptors
| Topological Polar Surface Area | 20.23 Ų💻 Computed |
| H-Bond Donors | 1 count💻 Computed |
| H-Bond Acceptors | 1 count💻 Computed |
| Rotatable Bonds | 5 count💻 Computed |
| Aromatic Rings | 0 count💻 Computed |
| Molar Refractivity | 40.704 cm^3/mol📊 OPERA |
| Polarizability | 16.137 Å^3📊 OPERA |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
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