Maltyl isobutyrate (CAS 65416-14-0) — Sweet Top to middle Note Fragrance Ingredient

Sweet · Balsamic

Maltyl isobutyrate

CAS 65416-14-0

Origin
synthetic
Note
Top to middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Maltyl isobutyrate?

Maltyl isobutyrate is a synthetic fragrance compound used to add rich, caramelized notes to perfumes and flavored products. You’ll encounter it in gourmand fragrances and some food flavorings. This ingredient matters because it creates warm, comforting scents reminiscent of baked goods and malted treats, adding depth to sweet compositions without being cloying.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major restrictions in current IFRA guidelines
Limited toxicological data available
CAS
65416-14-0
Formula
Mixture
MW
Variable
Odor Family
Sweet · Balsamic
Layer 1 · Enthusiast

What Does Maltyl isobutyrate Smell Like?

Maltyl isobutyrate delivers an intense, warm aroma that evolves from an initial burst of caramelized sugar to a heart of toasted malt and butterscotch. The dry-down reveals a subtle nuttiness akin to roasted barley, with a lingering sweetness that never becomes syrupy. Imagine the crust of a perfectly baked brioche meeting the depth of malted milkshake syrup, rounded out by a whisper of toasted hazelnuts.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Maltyl isobutyrate is an ester formed from maltol and isobutyric acid. As a synthetic compound, it’s typically produced through esterification reactions under controlled conditions. The molecule’s structure allows for both volatile top notes and persistent sweet characteristics. While not found in nature, it mimics compounds formed during Maillard reactions in cooked foods.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
Odor ThresholdExtremely low (high potency)

Perfumer Guide

Note Position
Top to middle
Volatility
Medium (1-3 hours)
Blending
Good with vanillic and spicy notes
ApplicationTypical %RangeNotes
Fine Fragrance0.1-1%Up to 2%Powerful modifier for gourmand accords
Functional Fragrance0.01-0.5%Up to 1%Adds warmth to air fresheners
Flavor5-50 ppmUp to 100 ppmBakery and confectionery applications

Classic Accords

Tip: Use sparingly in alcohol bases as it can overwhelm other notes at high concentrations.

Alternatives & Comparisons

1
Ethyl Maltol CAS 4940-11-8

For simpler sweetening effects without the toasted depth

2
Furaneol CAS 3658-77-3

When more strawberry-like caramel notes are desired

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific restrictions under current IFRA standards (as of 2023).

RIFM Assessment

Not currently evaluated by RIFM, but structurally similar compounds show low toxicity profiles.

Sustainability

As a synthetic material, maltyl isobutyrate doesn’t rely on agricultural resources. Production typically uses petrochemical feedstocks, though some manufacturers are exploring bio-based routes. Its high potency means minimal quantities are needed, reducing overall environmental impact compared to less powerful alternatives.

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References

  1. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.
  2. IFRA Standards Library (2023) IFRA Website

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Layer 3 · Practical

  • Odor Profile: caramellic, strawberry, sweet
  • FEMA GRAS: 3462

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