Methyl 3-(Furfurylthio)Propionate (CAS 94278-26-9) — Mid Note Fragrance Ingredient



fruity

Methyl 3-(Furfurylthio)Propionate

CAS 94278-26-9

Note
mid
Volatility
low
MW
200.2
Data as of: Jun 2026

What Is Methyl 3-(Furfurylthio)Propionate?

Methyl 3-(Furfurylthio)Propionate (CAS 94278-26-9) is an aroma chemical used as a fragrance and flavour ingredient. Its odour is described as bakery, fish and garlic, placing it within the fruity family as a mid note with low volatility. With a molecular weight of 200.2 (formula C9H12O3S), it is handled by perfumers as a building block for compositions where a bakery character is desired. The data below is compiled from public chemical and regulatory sources.

Safety Profile

USE WITH AWARENESS

Generally safeUse with awarenessProfessional use
CAS
94278-26-9
Formula
C9H12O3S
MW
200.2
InChIKey
MXXNUXUTQGTBGJ-UHFFFAOYSA-N
Methyl 3-(Furfurylthio)Propionate 2D structure

Methyl 3-(Furfurylthio)Propionate
C9H12O3S
Layer 1 · Enthusiast

What Does Methyl 3-(Furfurylthio)Propionate Smell Like?

The odour profile of Methyl 3-(Furfurylthio)Propionate is reported as bakery, fish, garlic, spices, cold, sour, burnt, acid, warm, musky, sweaty, ammonia/urinous, decayed, wood, grass, flower, chemical, edible, roasted. The dominant facet is its bakery character, with the remaining notes adding nuance and complexity. As a mid note it contributes to the heart of a fragrance. Perceived intensity and exact character depend on concentration, the carrier and the surrounding accord.

Scent Profile

Profile derived from public odour-descriptor data; relative, not absolute.

Layer 2

Chemistry & Properties

The Chemistry

Methyl 3-(Furfurylthio)Propionate has the molecular formula C9H12O3S and a molecular weight of 200.2 g/mol. Its canonical SMILES representation is COC(=O)CCSCC1=CC=CO1. Its reported log P (XLogP) of 2.08 indicates a lipophilic, oil-soluble molecule, which informs how it partitions in a formula. Physical constants below are drawn from PubChem and EPA CompTox public datasets.

Physical & Chemical Properties

Molecular Weight 200.2 g/mol
Boiling Point 260.0 °C
Melting Point 36.05 °C
Flash Point 119.5 °C
Density 1.51 g/cm³
Vapor Pressure 0.00341 mmHg
Water Solubility 0.005398 g/L
XLogP 2.08

Perfumer Guide

Note Position
Mid
Volatility
Low
Primary Odour
Bakery

Alternatives & Comparisons

Ingredients occupying a similar odour space — useful as substitutes or companions when Methyl 3-(Furfurylthio)Propionate is unavailable or restricted.

1
Isopentylamine CAS 107-85-7

Shares bakery, sweet, fish character — a candidate substitute or companion in the same odour space.

2
2,2'-(Thiodimethylene)-Difuran CAS 13678-67-6

Shares bakery, fruit, fish character — a candidate substitute or companion in the same odour space.

3
2-Acetyl-3-Ethylpyrazine CAS 32974-92-8

Shares bakery, sweet, fish character — a candidate substitute or companion in the same odour space.

Layer 3

Safety & Regulatory

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH and EU Cosmetics Regulation standards update periodically. Consult the current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

No IFRA restriction recorded in the data set. This is not a guarantee of unrestricted status — always confirm against the current IFRA Standards Library.

GHS Classification

Signal word: Warning

H315H319H335
Formulating with Methyl 3-(Furfurylthio)Propionate?

Open Methyl 3-(Furfurylthio)Propionate in Fragrance Studio (Pro) for the calibrated vapour-pressure curve, the modelled odour-threshold estimate, and the substitute-matching engine across 2,900+ aromachemicals.

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References & Sources

  1. PubChem Compound Summary (NIH) — search by InChIKey
  2. EPA CompTox Chemicals Dashboard — physicochemical & fate data
  3. IFRA Standards Library (49th / 51st Amendment)
Sources: PubChem (NIH) · EPA CompTox · IFRA Standards Library · public GHS classification. Odour descriptors are original editorial summaries of public profiles, not reproduced from any single proprietary source.

Data: PubChem (NIH), EPA CompTox, IFRA. Last reviewed: Jun 2026.

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