Phenol, 2-(1,1-dimethylethyl)-5-methyl- (CAS 88-60-8) — Woody Base Note Fragrance Ingredient
Phenol, 2-(1,1-dimethylethyl)-5-methyl-
CAS 88-60-8
What Is Phenol, 2-(1,1-dimethylethyl)-5-methyl-?
This synthetic fragrance ingredient is a specialized chemical compound primarily used in industrial and niche perfumery. Consumers might encounter it in certain woody or medicinal fragrance compositions. While not common in mainstream products, it serves as a building block for creating unique scent profiles that require specific aromatic characteristics.
Safety Profile
USE WITH AWARENESSWhat Does Phenol, 2-(1,1-dimethylethyl)-5-methyl- Smell Like?
This compound presents a sharp, phenolic character with underlying woody and slightly medicinal nuances. The initial impression is intense and somewhat harsh, evolving into a drier, more subdued woody note over time. In dilution, it can contribute a leathery or smoky facet to fragrance compositions, though it requires careful blending to avoid overpowering other elements.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Chemistry, Properties & Perfumer Guide
The Chemistry
This substituted phenol belongs to the alkylphenol class of aromatic compounds. The tert-butyl and methyl substituents on the phenolic ring create steric hindrance that influences both its chemical reactivity and odor properties. While naturally occurring phenols are widespread in plants, this particular substitution pattern is typically achieved through synthetic organic chemistry routes involving Friedel-Crafts alkylation reactions.
Physical & Chemical Properties
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Industrial Fragrances | 0.1-0.5% | Up to 1% | Used as modifier in small quantities |
| Niche Perfumery | 0.01-0.1% | Up to 0.3% | For avant-garde compositions |
Classic Accords
Tip: Use in trace amounts and always pre-dilute due to its potent phenolic character.
Alternatives & Comparisons
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not currently restricted by IFRA standards.
GHS Classification
RIFM Assessment
No RIFM assessment currently available for this specific compound.
Sustainability
As a synthetic material, this compound’s environmental impact depends on manufacturing processes. While it doesn’t rely on natural resources, its production requires petrochemical feedstocks and energy-intensive processes. Proper handling and disposal are important due to its phenolic nature.
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