Phenol, 4-(3,6-dihydro-4-methyl-2H-pyran-2-yl)-2-methoxy- (CAS 128489-02-1) — Woody Heart to base Note Fragrance Ingredient
Phenol, 4-(3,6-dihydro-4-methyl-2H-pyran-2-yl)-2-methoxy-
CAS 128489-02-1
What Is Phenol, 4-(3,6-dihydro-4-methyl-2H-pyran-2-yl)-2-methoxy-?
This synthetic fragrance ingredient is a specialized compound used in modern perfumery to create unique olfactory effects. It’s found in niche and experimental fragrances. The molecule’s complex structure allows perfumers to craft novel scent profiles that can’t be achieved with natural materials alone.
Safety Profile
USE WITH AWARENESSWhat Does Phenol, 4-(3,6-dihydro-4-methyl-2H-pyran-2-yl)-2-methoxy- Smell Like?
This synthetic molecule presents an intriguing duality – it opens with a sharp, almost medicinal phenolic character that quickly softens into a warm, slightly sweet woody-mossy core. The methoxy group lends a subtle powdery nuance, while the dihydropyran moiety contributes a faintly herbal, tea-like quality. As it dries down, the fragrance evolves into a sophisticated base reminiscent of sun-warmed oak barrels with a whisper of dried tobacco leaves.
Chemistry, Properties & Perfumer Guide
The Chemistry
This synthetic phenol derivative belongs to the class of methoxyphenols with a dihydropyran substitution. The molecule features a methoxy group at the 2-position and a 3,6-dihydro-4-methyl-2H-pyran moiety at the 4-position of the phenolic ring. Its synthesis typically involves the condensation of appropriately substituted phenols with dihydropyran precursors under acidic conditions. The compound’s stereochemistry may influence its olfactory properties, though specific data on chiral forms is currently limited in published literature.
Physical & Chemical Properties
| Appearance | Not documented |
|---|---|
| Color | Not documented |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-2% | Up to 5% | Used as a modifier in woody compositions |
| Functional Fragrance | 0.1-0.5% | Up to 1% | Restricted use in consumer products |
Classic Accords
Tip: Use sparingly to add phenolic depth to woody bases without overwhelming the composition.
Alternatives & Comparisons
Simpler phenolic alternative with smoky character, used when less complexity is desired.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No specific IFRA restrictions found. General phenol guidelines apply.
RIFM Assessment
Full safety assessment not yet completed by RIFM.
Sustainability
As a synthetic material, this ingredient’s production avoids natural resource depletion but requires careful assessment of chemical synthesis routes for environmental impact. The specialized nature of its production suggests moderate energy inputs and potential for byproduct formation that requires proper management.
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