Tetrahydrolinalyl acetate (CAS 20780-48-7) — Floral Top to Heart Note Fragrance Ingredient
Tetrahydrolinalyl acetate
CAS 20780-48-7
What Is Tetrahydrolinalyl acetate?
Tetrahydrolinalyl acetate is a synthetic fragrance ingredient used to add fresh, floral, and slightly fruity notes to perfumes. It’s commonly found in personal care products like shampoos, soaps, and fine fragrances. This ingredient helps create a clean, uplifting scent profile that blends well with citrus and floral notes, making it versatile for various applications.
Safety Profile
GENERALLY SAFEWhat Does Tetrahydrolinalyl acetate Smell Like?
Tetrahydrolinalyl acetate offers a fresh, floral scent with a hint of fruitiness, reminiscent of blooming gardens in spring. It starts with a bright, slightly citrusy top note that evolves into a soft, floral heart. The dry-down is clean and slightly woody, making it a versatile ingredient for fresh and floral fragrances.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used to enhance the floral freshness, blending seamlessly with citrus top notes.
Adds a clean, uplifting floral note to the heart of the fragrance.
2D Molecular Structure
SMILES: CCC(C)(CCCC(C)C)OC(C)=O
Chemistry, Properties & Perfumer Guide
The Chemistry
Tetrahydrolinalyl acetate is a synthetic ester derived from linalool. It is commonly used in perfumery for its fresh, floral scent. The compound is typically synthesized through the hydrogenation of linalyl acetate, resulting in a more stable and less volatile version of the original molecule.
Physical & Chemical Properties
| Boiling Point | N/A |
|---|---|
| Density | N/A |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 5-10% | Up to 15% | Adds fresh floral notes |
| Personal Care | 2-5% | Up to 10% | Provides clean scent |
Classic Accords
Tip: Use in floral and fresh accords to enhance cleanliness and brightness.
Alternatives & Comparisons
A natural alternative with a similar floral scent but higher volatility.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not restricted by IFRA.
EU Allergen Declaration
Not listed as an EU allergen.
RIFM Assessment
RIFM has evaluated this ingredient and found it safe for use in current applications.
Sustainability
Tetrahydrolinalyl acetate is synthesized from petrochemical sources, making it consistent in quality but less sustainable than natural alternatives. Efforts are being made to develop greener synthesis methods.
Explore Tetrahydrolinalyl acetate
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References
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data errorPhysicochemical Properties
DTXSID: DTXSID5041487
Physical Properties
| Molecular Weight | 200.322 g/mol🔬 EPA CompTox |
| Density | 0.866 g/cm^3🔬 EPA CTX |
| Boiling Point | 220.55 °C📊 OPERA |
| Melting Point | -37.132 °C📊 OPERA |
| Flash Point | 86.5 °C🔬 EPA CTX |
| Refractive Index | 1.428 Dimensionless📊 OPERA |
| Molar Volume | 230.524 cm^3/mol📊 OPERA |
Partition & Solubility
| LogP (Octanol-Water) | 5.6 Log10 unitless🔬 EPA CTX |
| LogD (pH 5.5) | 4.663 Log10 unitless📊 OPERA |
| LogD (pH 7.4) | 4.663 Log10 unitless📊 OPERA |
| LogKoa (Octanol-Air) | 5.78 Log10 unitless📊 OPERA |
| Water Solubility | 0 mol/L📊 OPERA |
| Henry's Law Constant | 0 atm-m3/mole📊 OPERA |
Transport Properties
| Vapor Pressure | 0.176 mmHg🔬 EPA CTX |
| Viscosity | 2.02 cP📊 OPERA |
| Surface Tension | 26.144 dyn/cm📊 OPERA |
| Thermal Conductivity | 126.303 mW/(m*K)📊 OPERA |
Molecular Descriptors
| Topological Polar Surface Area | 26.3 Ų💻 Computed |
| H-Bond Donors | 0 count💻 Computed |
| H-Bond Acceptors | 2 count💻 Computed |
| Rotatable Bonds | 6 count💻 Computed |
| Aromatic Rings | 0 count💻 Computed |
| Molar Refractivity | 59.342 cm^3/mol📊 OPERA |
| Polarizability | 23.525 Å^3📊 OPERA |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
