Tricyclo[5.2.1.02,6]dec-4-en-8-yl acetate (CAS 2500-83-6) — Woody Middle to base Note Fragrance Ingredient

ByThe Good Scents
Woody · Balsamic

Tricyclo[5.2.1.02,6]dec-4-en-8-yl acetate

CAS 2500-83-6

Origin
synthetic
Note
Middle to base
IFRA
Use with awareness
Data as of: Apr 2026

What Is Tricyclo[5.2.1.02,6]dec-4-en-8-yl acetate?

Tricyclo[5.2.1.02,6]dec-4-en-8-yl acetate is a synthetic fragrance ingredient used in modern perfumery. It’s found in woody and amber compositions, often adding depth to masculine fragrances. This molecule contributes a sophisticated, long-lasting character to scents, prized for its ability to enhance other ingredients without overpowering them.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
✓ IFRA compliant at standard usage levels
⚠ Limited safety data available
CAS
2500-83-6
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does Tricyclo[5.2.1.02,6]dec-4-en-8-yl acetate Smell Like?

A complex woody-amber note with subtle pine-like freshness. Opens with crisp camphoraceous facets that evolve into a smooth, slightly sweet woody heart. The dry-down reveals remarkable tenacity, leaving a refined cedar-like trail with hints of dry earthiness. Comparable to freshly split cedarwood with a whisper of damp forest floor.

Scent Profile
Layer 2

2D Molecular Structure

3a,4,5,6,7,7a-Hexahydro-1H-4,7-methanoinden-5-yl acetate

SMILES: CC(=O)OC1CC2CC1C1C=CCC21

Chemistry, Properties & Perfumer Guide

The Chemistry

A bicyclic terpenoid acetate with a complex fused ring structure. Synthesized through Diels-Alder reactions of cyclopentadiene derivatives followed by acetylation. The rigid molecular framework contributes to its excellent stability and longevity in fragrance applications. The acetate group provides subtle sweetness while the tricyclic core delivers robust woody character.

Physical & Chemical Properties

Perfumer Guide

Note Position
Middle to base
Volatility
Medium (2-6 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Woody accord enhancer
Functional Fragrance0.5-1.5%Up to 3%Long-lasting woody note

Classic Accords

Tip: Use as a fixative in woody compositions where subtle amber-like sweetness is desired.

Alternatives & Comparisons

1
Cedryl acetate CAS 77-54-3

More pronounced cedar character with similar longevity but less amber nuance.

2
Vertofix Coeur CAS 68039-49-6

Woody-amber alternative with smoother, more rounded profile.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA. Listed on IFRA Transparency List.

RIFM Assessment

Limited safety assessment available. Considered safe at current usage levels.

Sustainability

Synthetic production minimizes environmental impact compared to natural wood extracts. Manufacturing process optimized for atom economy. No known ecological concerns at current production scales.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

    Report a data error

    Perfumers Notes

    Odor Profile

    Anisic, green, sweet, woody.

    Standard Dilution

    10% in DPG (standard dilution for most fragrance materials)

    Ingredient Data Sheet

    CAS 2500-83-6

    Physical Properties

    Molecular Weight192.25 g/mol🔬 PubChem
    LogP (Octanol-Water)2.2🔬 PubChem
    Boiling Point262 °C🔬 EPA CompTox
    Vapor Pressure0.0021 mmHg @ 25°C📊 OPERA
    Flash Point101.8 °C🔬 EPA CompTox
    Involatility Index0.0002💻 Calculated
    log Kp (skin permeability)-2.311💻 Calculated
    SMILESCC(=O)OC1CC2CC1C3C2CC=C3🔬 PubChem

    Volatility & Performance

    Fragrance NoteBase💻 Calculated
    Volatility ClassVery slow💻 Calculated
    Persistence Score4.5 / 5💻 Calculated

    Odor & Flavor

    Primary Descriptorsgreensweetwoody• leffingwell
    Functional Groupsesteretheralkene💻 RDKit
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID3051917

    Physical Properties

    Molecular Weight 192.258 g/mol🔬 EPA CompTox
    Density 1.117 g/cm^3📊 OPERA
    Boiling Point 262.24 °C📊 OPERA
    Melting Point 93.828 °C📊 OPERA
    Flash Point 114.477 °C📊 OPERA
    Refractive Index 1.536 Dimensionless📊 OPERA
    Molar Volume 170.285 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 2.606 Log10 unitless📊 OPERA
    LogD (pH 5.5) 2.606 Log10 unitless📊 OPERA
    LogD (pH 7.4) 2.606 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 5.79 Log10 unitless📊 OPERA
    Water Solubility 0.005 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0.007 mmHg📊 OPERA
    Viscosity 9.743 cP📊 OPERA
    Surface Tension 37.022 dyn/cm📊 OPERA
    Thermal Conductivity 116.379 mW/(m*K)📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 26.3 Ų💻 Computed
    H-Bond Donors 0 count💻 Computed
    H-Bond Acceptors 2 count💻 Computed
    Rotatable Bonds 1 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 53.135 cm^3/mol📊 OPERA
    Polarizability 21.064 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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