3-Phenylpropionaldehyde (CAS 104-53-0) — Sweet Heart Note Fragrance Ingredient

Sweet · Floral

3-Phenylpropionaldehyde

CAS 104-53-0

Origin
synthetic
Note
Heart
IFRA
Use with awareness
Data as of: Apr 2026

What Is 3-Phenylpropionaldehyde?

3-Phenylpropionaldehyde is a synthetic fragrance ingredient with a sweet, floral-honey scent. You’ll encounter it in perfumes, soaps, and candles where it adds depth to floral compositions. This molecule matters because it mimics natural floral aromas at a fraction of the cost, allowing affordable luxury in everyday products while maintaining consistent quality.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
IFRA approved for most applications
Potential skin sensitizer at high concentrations
CAS
104-53-0
Formula
Mixture
MW
Variable
Odor Family
Sweet · Floral
Layer 1 · Enthusiast

What Does 3-Phenylpropionaldehyde Smell Like?

3-Phenylpropionaldehyde opens with an intense honeyed sweetness, like crystallized nectar dripping from a comb, quickly unfolding into a floral heart reminiscent of lilac and hyacinth drenched in golden sunlight. As it dries, the aroma develops a subtle cinnamon-spiced warmth, leaving a lingering impression of crushed flower stems and vanilla-infused tobacco. The transition from syrupy top notes to powdery-woody base creates remarkable diffusion that fills space without overwhelming.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

J'adore(Dior, 1999)

Used as a honeyed floral bridge between the bright bergamot top and ylang-ylang heart, amplifying the solar floral effect while adding diffusion-enhancing sweetness.

Chance Eau Tendre(Chanel, 2010)

Provides a candied floralcy that softens the citrus-quince opening and blends seamlessly into the white musk drydown, creating the ‘tender’ effect.

Layer 2

2D Molecular Structure

3-Phenylpropanal

SMILES: O=CCCC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

3-Phenylpropionaldehyde belongs to the phenylpropanoid class, featuring a benzene ring connected to an aldehyde group via a three-carbon chain. While found in trace amounts in some flowers, commercial production typically involves the oxidation of cinnamyl alcohol or hydroformylation of styrene. The molecule lacks chirality centers, ensuring consistent olfactory properties across synthetic batches. Its conjugated π-electron system contributes to both chemical stability and intense odor characteristics.

Physical & Chemical Properties

Boiling Point222 °C
Density1.010 g/cm³
Refractive Index1.520-1.525
Flash Point101 °C

Perfumer Guide

Note Position
Heart
Volatility
Medium (2-6 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Floral modifier
Soap0.1-0.5%Up to 1%Sweetness booster

Classic Accords

Tip: Stabilize in ethanol before adding to aqueous systems to prevent Schiff base formation.

Alternatives & Comparisons

1
Phenylacetaldehyde CAS 122-78-1

More green-floral with less honeyed sweetness, useful when requiring sharper floral definition without gourmand effects.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific restrictions under IFRA 51st Amendment. General usage guidelines apply.

EU Allergen Declaration

Not listed in EU allergen regulation (EC) No 1223/2009 Annex III.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

RIFM evaluation complete – safe at current use levels with proper handling precautions.

Sustainability

Synthetic production from petrochemical feedstocks raises carbon footprint concerns, but high potency reduces per-wear environmental impact compared to natural extracts. No animal derivatives or endangered plant materials involved.

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References

  1. Bauer et al. (2001). Common Fragrance and Flavor Materials. Wiley-VCH.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID0047610

Physical Properties

Molecular Weight 134.178 g/mol🔬 EPA CompTox
Density 1.012 g/cm^3🔬 EPA CTX
Boiling Point 224.5 °C🔬 EPA CTX
Melting Point -14.5 °C🔬 EPA CTX
Flash Point 95.075 °C🔬 EPA CTX
Refractive Index 1.509 Dimensionless📊 OPERA
Molar Volume 136.076 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 1.929 Log10 unitless📊 OPERA
LogD (pH 5.5) 1.929 Log10 unitless📊 OPERA
LogD (pH 7.4) 1.929 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 4.85 Log10 unitless📊 OPERA
Water Solubility 0.016 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.181 mmHg📊 OPERA
Viscosity 1.837 cP📊 OPERA
Surface Tension 35.479 dyn/cm📊 OPERA
Thermal Conductivity 145.592 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 3 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 40.622 cm^3/mol📊 OPERA
Polarizability 16.104 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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