Isoeugenyl methyl ether (CAS 93-16-3) — Spicy Middle Note Fragrance Ingredient

ByThe Good Scents
Spicy · Balsamic

Isoeugenyl methyl ether

CAS 93-16-3

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is Isoeugenyl methyl ether?

Isoeugenyl methyl ether is a synthetic fragrance ingredient used in perfumes and scented products. It provides a warm, spicy, and clove-like aroma. This ingredient is valued for its long-lasting scent and ability to enhance floral and oriental fragrance compositions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
✓ Safe in regulated products
⚠ Known allergen – check labels
CAS
93-16-3
Formula
Mixture
MW
Variable
Odor Family
Spicy · Balsamic
Layer 1 · Enthusiast

What Does Isoeugenyl methyl ether Smell Like?

Isoeugenyl methyl ether offers a rich, spicy aroma with clove-like warmth and a hint of floral sweetness. Initially intense and slightly medicinal, it evolves into a smooth, woody base. The dry-down is long-lasting, leaving a comforting, slightly powdery trail reminiscent of vintage perfumes.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Opium(Yves Saint Laurent, 1977)

Used for its spicy warmth, enhancing the oriental accord and adding depth to the floral heart.

Cinnabar(Estée Lauder, 1978)

Adds a clove-like spice to the rich amber and floral notes, creating a bold, exotic character.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Isoeugenyl methyl ether is a synthetic aromatic compound derived from isoeugenol. It belongs to the phenylpropanoid class, commonly used in perfumery for its spicy, clove-like scent. The compound is typically synthesized via methylation of isoeugenol, resulting in a more stable and longer-lasting fragrance ingredient.

Physical & Chemical Properties

Boiling PointN/A
DensityN/A

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 10%Adds spicy depth
Home Fragrance0.5-3%Up to 5%Warm, inviting atmosphere

Classic Accords

Tip: Use sparingly to avoid overpowering other notes.

Alternatives & Comparisons

1
Eugenol CAS 97-53-0

A natural alternative with similar spicy notes but higher volatility.

2
Isoeugenol CAS 97-54-1

Provides a more intense clove-like aroma, suitable for stronger formulations.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA.

EU Allergen Declaration

May cause allergic reactions in some individuals.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

Under review by RIFM for safety assessment.

Sustainability

Synthetic production ensures consistent quality and reduces reliance on natural resources. Environmental impact is minimized through regulated manufacturing processes.

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References

  1. PubChem: Isoeugenyl methyl ether PubChem
  2. IFRA Standards IFRA

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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