L-Lactic acid (2-hydroxy propionic acid) (CAS 79-33-4) — Citrus Top to middle Note Fragrance Ingredient

Citrus · Sweet

L-Lactic acid (2-hydroxy propionic acid)

CAS 79-33-4

Origin
synthetic
Note
Top to middle
IFRA
Generally safe
Data as of: Apr 2026

What Is L-Lactic acid (2-hydroxy propionic acid)?

L-lactic acid is a naturally occurring organic acid found in foods like yogurt and sourdough bread, and also produced by our bodies during exercise. In fragrances, it’s used in tiny amounts to add subtle sour or tangy nuances. While not a major scent player itself, it helps create realistic fruit and dairy notes in perfumes and body products.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
GRAS (Generally Recognized As Safe)
Naturally present in human metabolism
CAS
79-33-4
Formula
Mixture
MW
Variable
Odor Family
Citrus · Sweet
Layer 1 · Enthusiast

What Does L-Lactic acid (2-hydroxy propionic acid) Smell Like?

L-lactic acid presents a clean, slightly sharp sourness reminiscent of fresh yogurt or buttermilk at full concentration, though it’s rarely used neat in perfumery. At dilution, it contributes a subtle tang that can enhance fruity top notes – particularly berry and citrus accords – with a naturalistic fermented quality. Unlike harsher synthetic acids, its odor profile remains smooth and slightly milky in the dry-down, blending well with lactonic and musky bases to create skin-like warmth.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

L-lactic acid (2-hydroxypropanoic acid) is the levorotatory enantiomer of this α-hydroxy acid, differing from its D-form counterpart in optical rotation and some biological interactions. While naturally produced via bacterial fermentation of sugars, fragrance applications typically use synthetic versions for consistency. Industrial production involves chemical synthesis from acetaldehyde and hydrogen cyanide followed by hydrolysis, or increasingly via bioengineering methods using genetically modified microorganisms for sustainable production.

Physical & Chemical Properties

Boiling Point122 °C (at 15 mmHg)
Melting Point52-54 °C
Density1.206 g/cm³ (at 20 °C)
SolubilityMiscible in water, ethanol

Perfumer Guide

Note Position
Top to middle
Volatility
Medium (2-4 hours)
Blending
Moderate
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%As a modifier in fruit accords
Body Products0.5-2%Up to 5%For pH adjustment and subtle tang
Functional Fragrances0.01-0.1%Trace amountsTo enhance freshness in detergents

Classic Accords

Tip: Use in micro-doses with ionones to create nuanced strawberry effects without harshness.

Alternatives & Comparisons

1
DL-Lactic acid CAS 50-21-5

Racemic mixture offering similar sourness at lower cost, though slightly less refined in odor profile.

2
Gluconolactone CAS 90-80-2

Gentler acid with slower release, useful for extended-release sour notes in functional products.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not restricted by IFRA – considered safe at all typical usage levels in fragrance applications.

GHS Classification

H315 Skin irritation

RIFM Assessment

RIFM evaluation confirms safety in cosmetic applications at current use levels.

Sustainability

Increasingly produced via sustainable fermentation processes using agricultural byproducts as feedstock. Synthetic routes remain common but carry higher carbon footprint. Biodegradable and non-bioaccumulative, posing minimal environmental risk at fragrance usage levels.

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References

  1. PubChem Compound Summary for L-Lactic acid PubChem CID: 107689
  2. EFSA Panel on Food Additives (2015). Safety of lactic acid for use in foods. EFSA Journal 13(11):4241

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Perfumer’s Notes

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