Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-D-glucopyranoside (4:1) (CAS 61849-72-7) — Citrus N/A Note Fragrance Ingredient
Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-D-glucopyranoside (4:1)
CAS 61849-72-7
What Is Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-D-glucopyranoside (4:1)?
This synthetic ingredient is a specialized polymer used primarily in cosmetic formulations and industrial applications. Consumers may encounter it in hair care products and skin moisturizers where it functions as a conditioning agent. While not a traditional fragrance material, it plays a supporting role in product performance by improving texture and delivery of scent components.
Safety Profile
GENERALLY SAFEWhat Does Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-D-glucopyranoside (4:1) Smell Like?
This polymer is essentially odorless, functioning primarily as a carrier or texturizing agent rather than contributing directly to fragrance profiles. Its molecular structure lacks volatile components that would produce detectable aroma.
2D Molecular Structure
SMILES: CO[C@H]1O[C@@H](COCCCO)[C@H](OCCCO)[C@@H](OCCCO)[C@@H]1OCCCO |r,lp:1:2,3:2,6:2,10:2,12:2,16:2,18:2,22:2,24:2,28:2,Sg:n:9,8,7,6::ht,Sg:n:15,14,13,12::ht,Sg:n:21,20,19,18::ht,Sg:n:27,26,25,24::ht|
Chemistry, Properties & Perfumer Guide
The Chemistry
This polymer belongs to the class of polyethylene glycol derivatives modified with glucoside groups. The structure combines hydrophilic polyether chains with sugar moieties, creating amphiphilic properties. Synthesis typically involves controlled polymerization of ethylene oxide followed by grafting with methyl glucoside. The 4:1 ratio indicates the stoichiometry between the polyether backbone and sugar units.
Physical & Chemical Properties
| Appearance | Clear viscous liquid |
|---|---|
| Solubility | Water-soluble |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Hair Care | 1-3% | 0.5-5% | Conditioning agent |
| Skin Care | 0.5-2% | 0.1-3% | Moisturizing matrix |
Classic Accords
Tip: Use as a solubilizer for hydrophilic fragrance components in aqueous systems.
Alternatives & Comparisons
Offers similar solubilizing properties with additional emollient effects from fatty acid chains.
More economical surfactant with comparable hydrophilic-lipophilic balance for fragrance solubilization.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not restricted by IFRA as it is not a fragrance material.
RIFM Assessment
Not evaluated by RIFM as it is not a fragrance material.
Sustainability
As a synthetic polymer, this material is produced through controlled chemical processes with minimal environmental impact. Being water-soluble, it poses low bioaccumulation risk. The production can be optimized for atom economy given the well-established ethylene oxide polymerization technology.
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References
- Cosmetic Ingredient Review Expert Panel (Year). Safety Assessment of Alkyl PEG Ethers. International Journal of Toxicology.
- Personal Care Product Council. International Nomenclature of Cosmetic Ingredients.
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data errorIngredient Data Sheet
CAS 61849-72-7Physical Properties
| Molecular Weight | 426.5 g/mol🔬 PubChem |
| LogP (Octanol-Water) | -1.8🔬 PubChem |
| log Kp (skin permeability) | -6.58💻 Calculated |
| SMILES | COC1C(C(C(C(O1)COCCCO)OCCCO)OCCCO)OCCCO🔬 PubChem |
Odor & Flavor
| Functional Groups | alcoholether💻 RDKit |
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.
Physicochemical Properties
DTXSID: DTXSID30977418
Physical Properties
| Molecular Weight | 426.5 g/mol🔬 PubChem |
Partition & Solubility
| LogP (Octanol-Water) | -0.94 dimensionless💻 Computed |
Molecular Descriptors
| Topological Polar Surface Area | 136.3 Ų💻 Computed |
| H-Bond Donors | 4 count💻 Computed |
| H-Bond Acceptors | 10 count💻 Computed |
| Rotatable Bonds | 18 count💻 Computed |
| Aromatic Rings | 0 count💻 Computed |
| Molar Refractivity | 102.52 cm^3/mol💻 Computed |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
