2-Methylpentanal (CAS 123-15-9) — Green Top Note Fragrance Ingredient

Green · Citrus

2-Methylpentanal

CAS 123-15-9

Origin
synthetic
Note
Top
IFRA
Use with awareness
Data as of: Apr 2026

What Is 2-Methylpentanal?

2-Methylpentanal is a synthetic fragrance ingredient with a distinctive green, leafy aroma. You’ll encounter it in perfumes, especially those aiming for fresh, natural green notes. This aldehyde matters because it can mimic the crispness of crushed leaves or unripe fruit at minute concentrations, adding realism to nature-inspired fragrances.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
IFRA-compliant at standard usage levels
Potential skin sensitizer at high concentrations
CAS
123-15-9
Formula
Mixture
MW
Variable
Odor Family
Green · Citrus
Layer 1 · Enthusiast

What Does 2-Methylpentanal Smell Like?

2-Methylpentanal bursts with an intensely green, almost aggressive top note reminiscent of freshly torn grass blades and broken tomato vines. The initial sharpness mellows into a cucumber-like watery freshness, with subtle undertones of unripe apples. In drydown, it leaves a faint waxy-green trail, behaving like a more tenacious version of leaf alcohol but with greater diffusion.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Vent Vert(Balmain, 1947)

Used to amplify the hyper-realistic crushed galbanum effect, contributing razor-sharp greenness that defines this legendary chypre’s opening.

Provides the wet vegetal accent that mimics monsoon-drenched foliage, blending with ginger and cardamom for a rain-soaked garden effect.

Layer 2

2D Molecular Structure

2-Methylpentanal

SMILES: CCCC(C)C=O

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Methylpentanal is a branched-chain aldehyde (C6H12O) produced industrially via hydroformylation of 2-methyl-1-pentene. Its structure features an α-branch that intensifies green character compared to linear hexanal. The molecule exists as enantiomers, with the (R)-form showing greater olfactory potency. Synthesis typically employs rhodium catalysts under controlled pressure, yielding material with <1% residual olefin content.

Physical & Chemical Properties

Boiling Point130-132 °C
Vapor Pressure12.3 mmHg at 25°C
Density0.815 g/cm³

Perfumer Guide

Note Position
Top
Volatility
Medium (1-3 hours)
Blending
Good with citrus and woody notes
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%Powerful green modifier
Functional Fragrance0.01-0.1%Up to 0.2%Freshness booster in detergents

Classic Accords

+ Galbanum + Violet Leaf = Hyper-green + Citronellol + Dihydromyrcenol = Shower gel freshness

Tip: Stabilize in ethanol before adding to water-based systems to prevent aldehyde polymerization.

Alternatives & Comparisons

1
Hexanal CAS 66-25-1

Less intense linear version for softer green effects, preferred in food flavors and delicate floral compositions.

2
(Z)-3-Hexenal CAS 6789-80-6

More transient but extremely natural ‘cut grass’ note, suitable for top note bursts in naturalistic fragrances.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific restrictions under IFRA 51st Amendment. General aldehyde precautions apply.

GHS Classification

H315 Skin irritation H319 Eye irritation H335 May cause respiratory irritation

RIFM Assessment

RIFM assessment complete (2019). Safe at current industry usage levels with recommended concentration limits.

Sustainability

Synthesized from petrochemical feedstocks but used at extremely low doses (typically <0.1%). Production employs efficient catalytic processes with >90% atom economy. No known ecological accumulation due to rapid atmospheric degradation (half-life <24h).

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References

  1. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press. ISBN 9781439810743

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID9021978

Physical Properties

Molecular Weight 100.161 g/mol🔬 EPA CompTox
Density 0.811 g/cm^3🔬 EPA CTX
Boiling Point 117.988 °C🔬 EPA CTX
Melting Point -100 °C🔬 EPA CTX
Flash Point 18.522 °C🔬 EPA CTX
Refractive Index 1.394 Dimensionless📊 OPERA
Molar Volume 125.271 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 1.8 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 1.693 Log10 unitless📊 OPERA
LogD (pH 7.4) 1.693 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 3.53 Log10 unitless📊 OPERA
Water Solubility 0.042 mol/L🔬 EPA CTX
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 19.617 mmHg🔬 EPA CTX
Viscosity 0.571 cP📊 OPERA
Surface Tension 23.811 dyn/cm📊 OPERA
Thermal Conductivity 137.043 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 3 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 29.992 cm^3/mol📊 OPERA
Polarizability 11.89 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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