Cyclohexanol,4-(3-methylbutyl)- (CAS 830322-14-0) — Woody Middle to base Note Fragrance Ingredient
Cyclohexanol,4-(3-methylbutyl)-
CAS 830322-14-0
What Is Cyclohexanol,4-(3-methylbutyl)-?
Cyclohexanol,4-(3-methylbutyl)- is a synthetic fragrance ingredient primarily used in modern perfumery to add woody and musky nuances. While not commonly recognized by name, it subtly enhances many personal care products and fine fragrances. This molecule matters because it helps perfumers create long-lasting, sophisticated scent profiles that evolve beautifully on skin, bridging the gap between fresh top notes and deep base accords.
Safety Profile
USE WITH AWARENESSWhat Does Cyclohexanol,4-(3-methylbutyl)- Smell Like?
A modern woody-musky workhorse with a surprisingly complex profile. Opens with a crisp, almost citrus-tinged freshness that rapidly settles into a smooth sandalwood-like heart. The dry down reveals subtle ambery undertones with a whisper of clean musk. Unlike traditional woody materials, it maintains an airy quality that prevents heaviness, making it ideal for contemporary compositions. Perfumers appreciate its chameleon-like ability to amplify both floral and oriental accords without overpowering them.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used here to create an ultra-modern green woody backbone that contrasts with the hyper-realistic galbanum and lily-of-the-valley notes, demonstrating its ability to bridge natural and synthetic elements seamlessly.
Contributes to the legendary ‘amorphous woody’ effect in this cult fragrance, helping create that elusive ‘your skin but better’ quality in the dry down.
2D Molecular Structure
SMILES: CC(C)CCC1CCC(O)CC1
Chemistry, Properties & Perfumer Guide
The Chemistry
This synthetic cyclohexanol derivative belongs to the family of saturated cyclic alcohols. While not found in nature, its structure draws inspiration from traditional sandalwood components. Industrially synthesized through catalytic hydrogenation of appropriate precursors, its purity and consistency make it valuable for modern perfumery applications. The branched alkyl chain provides both volatility control and enhanced tenacity compared to simpler cyclohexanol derivatives.
Physical & Chemical Properties
| Appearance | Colorless to pale yellow liquid |
|---|---|
| Boiling Point | Estimated ~250-280°C |
| Density | Estimated ~0.9 g/cm³ |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 1-5% | Up to 8% | Provides woody-musky foundation |
| Personal Care | 0.5-2% | Up to 3% | Used for subtle dry-down effects |
Classic Accords
Tip: Excellent for smoothing rough edges in woody-ambery bases while maintaining transparency.
Alternatives & Comparisons
When a more pronounced woody character is needed, though less musky. Good for masculine fragrances requiring more definition.
For a richer, more natural sandalwood effect, though significantly more expensive and potentially overpowering in high concentrations.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not currently restricted by IFRA. No specific usage limits established.
RIFM Assessment
Under evaluation by RIFM. Preliminary data suggests moderate safety profile at current usage levels.
Sustainability
As a fully synthetic material, production avoids natural resource depletion. Modern synthetic routes typically employ efficient catalytic processes with minimal byproducts. Being produced in controlled industrial settings allows for consistent quality and traceability throughout the supply chain.
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References
- IFRA Standards Library (2023). 49th Amendment. IFRA Standards
- Bickers et al. (2011). Safety assessment of fragrance materials. PMID 21793896
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data errorPhysicochemical Properties
DTXSID: DTXSID50889100
Physical Properties
| Molecular Weight | 170.296 g/mol🔬 EPA CompTox |
| Density | 0.89 g/cm^3🔬 EPA CTX |
| Boiling Point | 243.5 °C🔬 EPA CTX |
| Melting Point | 44.33 °C📊 OPERA |
| Flash Point | 111 °C🔬 EPA CTX |
| Refractive Index | 1.462 Dimensionless📊 OPERA |
| Molar Volume | 190.91 cm^3/mol📊 OPERA |
Partition & Solubility
| LogP (Octanol-Water) | 4.49 Log10 unitless🔬 EPA CTX |
| LogD (pH 5.5) | 3.514 Log10 unitless📊 OPERA |
| LogD (pH 7.4) | 3.514 Log10 unitless📊 OPERA |
| LogKoa (Octanol-Air) | 7.71 Log10 unitless📊 OPERA |
| Water Solubility | 0.002 mol/L📊 OPERA |
| Henry's Law Constant | 0 atm-m3/mole📊 OPERA |
Transport Properties
| Vapor Pressure | 0.005 mmHg🔬 EPA CTX |
| Viscosity | 11.053 cP📊 OPERA |
| Surface Tension | 30.084 dyn/cm📊 OPERA |
| Thermal Conductivity | 136.324 mW/(m*K)📊 OPERA |
Molecular Descriptors
| Topological Polar Surface Area | 20.23 Ų💻 Computed |
| H-Bond Donors | 1 count💻 Computed |
| H-Bond Acceptors | 1 count💻 Computed |
| Rotatable Bonds | 3 count💻 Computed |
| Aromatic Rings | 0 count💻 Computed |
| Molar Refractivity | 52.445 cm^3/mol📊 OPERA |
| Polarizability | 20.791 Å^3📊 OPERA |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
