Dihydro-4-methyl-5-pentylfuran-2(3H)-one (CAS 33673-62-0) — Sweet Heart Note Fragrance Ingredient

Sweet · Floral

Dihydro-4-methyl-5-pentylfuran-2(3H)-one

CAS 33673-62-0

Origin
synthetic
Note
Heart
IFRA
Generally safe
Data as of: Apr 2026

What Is Dihydro-4-methyl-5-pentylfuran-2(3H)-one?

Dihydro-4-methyl-5-pentylfuran-2(3H)-one is a synthetic fragrance ingredient used to add creamy, fruity nuances to perfumes. It’s found in luxury body lotions, candles, and fine fragrances. This compound matters because it mimics natural lactones found in fruits like peaches, enhancing sweetness without being cloying.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated concentrations
Potential skin sensitizer at high doses
CAS
33673-62-0
Formula
Mixture
MW
Variable
Odor Family
Sweet · Floral
Layer 1 · Enthusiast

What Does Dihydro-4-methyl-5-pentylfuran-2(3H)-one Smell Like?

A creamy, fruity aroma with peach-like sweetness and a hint of coconut. The scent evolves from initial juicy brightness to a smooth, lactonic richness. Dry-down reveals a soft, woody undertone that lingers subtly.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Peche Cardinal(MDCI, 2005)

Used to enhance the peach accord, providing a creamy depth that balances the floral heart.

Layer 2

2D Molecular Structure

2(3H)-Furanone, dihydro-4-methyl-5-pentyl-

SMILES: CCCCCC1OC(=O)CC1C

Chemistry, Properties & Perfumer Guide

The Chemistry

Dihydro-4-methyl-5-pentylfuran-2(3H)-one is a synthetic lactone. It belongs to the furanone class, known for their creamy, fruity odors. Typically synthesized via esterification or cyclization of appropriate precursors to achieve the desired olfactory profile.

Physical & Chemical Properties

Boiling PointN/A
DensityN/A

Perfumer Guide

Note Position
Heart
Volatility
Medium (2-6 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Adds creamy fruity nuances
Body Care0.5-2%Up to 3%Enhances sweetness in lotions

Classic Accords

Tip: Use sparingly to avoid overpowering other notes.

Alternatives & Comparisons

1
Gamma-Decalactone CAS 706-14-9

Natural alternative with similar creamy peach notes, but less intense.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions.

RIFM Assessment

RIFM assessment pending.

Sustainability

Synthetic production ensures consistent quality and reduces reliance on natural resources. Biodegradability studies are ongoing.

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References

  1. PubChem Compound Summary for Dihydro-4-methyl-5-pentylfuran-2(3H)-one PubChem

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID70865683

Physical Properties

Molecular Weight 170.252 g/mol🔬 EPA CompTox
Density 0.941 g/cm^3📊 OPERA
Boiling Point 251.145 °C📊 OPERA
Melting Point -8.278 °C📊 OPERA
Flash Point 105.872 °C📊 OPERA
Refractive Index 1.438 Dimensionless📊 OPERA
Molar Volume 183.34 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 2.941 Log10 unitless📊 OPERA
LogD (pH 5.5) 2.941 Log10 unitless📊 OPERA
LogD (pH 7.4) 2.941 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.73 Log10 unitless📊 OPERA
Water Solubility 0.008 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.026 mmHg📊 OPERA
Viscosity 2.902 cP📊 OPERA
Surface Tension 28.176 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 26.3 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 2 count💻 Computed
Rotatable Bonds 4 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 48.116 cm^3/mol📊 OPERA
Polarizability 19.075 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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